Recombinant Human SLC29A2 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC29A2-354H
• Product Overview: SLC29A2 MS Standard C13 and N15-labeled recombinant protein (NP_001523) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]). [supplied by OMIM, Nov 2008]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.1 kDa
• AA Sequence: MARGDAPRDSYHLVGISFFILGLGT LLPWNFFITAIPYFQARLAGAGNST ARILSTNHTGPEDAFNFNNWVTLLS QLPLLLFTLLNSFLYQCVPETVRIL GSLLAILLLFALTAALVKVDMSPGP FFSITMASVCFINSFSAVLQGSLFG QLGTMPSTYSTLFLSGQGLAGIFAA LAMLLSMASGVDAETSALGYFITPC VGILMSIVCYLSLPHLKFARYYLAN KSSQAQAQELETKAELLQSDENGIP SSPQKVALTLDLDLEKEPESEPDEP QKPGKPSVFTVFQKIWLTALCLVLV FTVTLSVFPAITAMVTSSTSPGKWS QFFNPICCFLLFNIMDWLGRSLTSY FLWPDEDSRLLPLLVCLRFLFVPLF MLCHVPQRSRLPILFPQDAYFITFM LLFAVSNGYLVSLTMCLAPRQVLPH EREVAGALMTFFLALGLSCGASLSF LFKALLTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC29A2 solute carrier family 29 (nucleoside transporters), member 2 [ Homo sapiens (human) ]
• Official Symbol: SLC29A2
• Synonyms: ENT2; DER12; HNP36
• Gene ID: 3177
• mRNA Refseq: NM_001532
• Protein Refseq: NP_001523
• MIM: 602110
• UniProt ID: Q14542