Recombinant Human SLC30A8 Protein, His&GST-tagged

• Cat.No.: SLC30A8-2073H
• Product Overview: Recombinant Human SLC30A8 Protein (Thr263-Asp369) with N-His&GST tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 41.7 kDa
  Accurate Molecular Mass: 42 kDa
• Protein length: Thr263-Asp369
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: SLC30A8 solute carrier family 30 (zinc transporter), member 8 [ Homo sapiens (human) ]
• Official Symbol: SLC30A8
• Synonyms: SLC30A8; solute carrier family 30 (zinc transporter), member 8; zinc transporter 8; zinc transporter ZnT-8; ZNT8; ZnT-8
• Gene ID: 169026
• mRNA Refseq: NM_001172811
• Protein Refseq: NP_001166282
• MIM: 611145
• UniProt ID: Q8IWU4