Recombinant Human SOD3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | SOD3-5394H |
Product Overview : | SOD3 MS Standard C13 and N15-labeled recombinant protein (NP_003093) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 25.9 kDa |
AA Sequence : | MLALLCSCLLLAAGASDAWTGEDSA EPNSDSAEWIRDMYAKVTEIWQEVM QRRDDDGTLHAACQVQPSATLDAAQ PRVTGVVLFRQLAPRAKLDAFFALE GFPTEPNSSSRAIHVHQFGDLSQGC ESTGPHYNPLAVPHPQHPGDFGNFA VRDGSLWRYRAGLAASLAGPHSIVG RAVVVHAGEDDLGRGGNQASVENGN AGRRLACCVVGVCGPGLWERQAREH SERKKRRRESECKAATRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | SOD3 superoxide dismutase 3 [ Homo sapiens (human) ] |
Official Symbol : | SOD3 |
Synonyms : | SOD3; superoxide dismutase 3, extracellular; extracellular superoxide dismutase [Cu-Zn]; EC SOD; EC-SOD; MGC20077; |
Gene ID : | 6649 |
mRNA Refseq : | NM_003102 |
Protein Refseq : | NP_003093 |
MIM : | 185490 |
UniProt ID : | P08294 |
Products Types
◆ Recombinant Protein | ||
SOD3-8570M | Recombinant Mouse SOD3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sod3-6042M | Recombinant Mouse Sod3 Protein, Myc/DDK-tagged | +Inquiry |
SOD3-5327R | Recombinant Rat SOD3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOD3-1235H | Recombinant Human SOD3 Protein, His-tagged | +Inquiry |
SOD3-4223R | Recombinant Rhesus Macaque SOD3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SOD3-1573HCL | Recombinant Human SOD3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionEnhancing SOD3 activity could be a therapeutic strategy in treating oxidative stress-related diseases.
Genetic mutations in SOD3 can impair its ability to scavenge free radicals, affecting its protective role.
It protects cells from oxidative damage by converting free radicals to less harmful substances.
Altered SOD3 activity is linked with accelerated aging and the development of age-related diseases.
SOD3 works alongside other antioxidants, contributing to the overall oxidative defense system.
SOD3, a type of superoxide dismutase, is crucial for neutralizing superoxide radicals, reducing oxidative stress.
SOD3 is important for cardiovascular health, preventing oxidative damage in blood vessels.
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Write a reviewTrusted for results accuracy. A research necessity.
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