Recombinant Human TDP1 Protein, Flag-tagged
Cat.No. : | TDP1-3326H |
Product Overview : | Recombinant Human TDP1 Protein, Transcript Variant 1, is produced by HEK293T expression system. This protein is fused with a Flag tag. |
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Description : | The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). |
Source : | HEK293 cells |
Species : | Human |
Tag : | Flag |
Form : | PBS buffer |
Molecular Mass : | 68 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Gene Name : | TDP1 tyrosyl-DNA phosphodiesterase 1 [ Homo sapiens ] |
Official Symbol : | TDP1 |
Synonyms : | TDP1; tyrosyl-DNA phosphodiesterase 1; FLJ11090; SCAN1; tyr-DNA phosphodiesterase 1; MGC104252; |
Gene ID : | 55775 |
mRNA Refseq : | NM_001008744 |
Protein Refseq : | NP_001008744 |
MIM : | 607198 |
UniProt ID : | Q9NUW8 |
Products Types
◆ Recombinant Protein | ||
TDP1-3325H | Recombinant Human TDP1 Protein, GST-tagged | +Inquiry |
TDP1-3327H | Recombinant Human TDP1 Protein, Flag-tagged | +Inquiry |
TDP1-5657R | Recombinant Rat TDP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDP1-4476R | Recombinant Rhesus Macaque TDP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDP1-3328H | Recombinant Human TDP1 Protein | +Inquiry |
◆ Lysates | ||
TDP1-1155HCL | Recombinant Human TDP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionInhibition of TDP1 expression induces apoptosis in gastric cancer cells.
TDP1 has been closely associated with the study of diseases such as gastric cancer and lung cancer.
Lung adenocarcinoma tissues expressed higher levels of TDP1 compared to paraneoplastic and normal tissues.
TDP1 is involved in DNA damage repair and plays a driving role in tumorigenesis and development.
Customer Reviews (3)
Write a reviewVery professional customer service, fully understanding the needs of the customer and giving professional advice.
The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.
Fast and timely shipment helped me to get satisfactory experimental results in short time.
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