Recombinant Human TDP1 Protein, GST-tagged

• Cat.No.: TDP1-3325H
• Product Overview: Recombinant Human TDP1 Protein (1-608 AA) is produced by Wheat Germ (in vitro) expression system. This protein is fused with a GST tag at the N-terminal.

Specification

• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 92.62 kDa
• Protein length: 1-608 AA
• AA Sequence: MSQEGDYGRWTISSSDESEEEKPKP DKPSTSSLLCARQGAANEPRYTCSE AQKAAHKRKISPVKFSNTDSVLPPK RQKSGSQEDLGWCLSSSDDELQPEM PQKQAEKVVIKKEKDISAPNDGTAQ RTENHGAPACHRLKEEEDEYETSGE GQDIWDMLDKGNPFQFYLTRVSGVK PKYNSGALHIKDILSPLFGTLVSSA QFNYCFDVDWLVKQYPPEFRKKPIL LVHGDKREAKAHLHAQAKPYENISL CQAKLDIAFGTHHTKMMLLLYEEGL RVVIHTSNLIHADWHQKTQGIWLSP LYPRIADGTHKSGESPTHFKADLIS YLMAYNAPSLKEWIDVIHKHDLSET NVYLIGSTPGRFQGSQKDNWGHFRL KKLLKDHASSMPNAESWPVVGQFSS VGSLGADESKWLCSEFKESMLTLGK ESKTPGKSSVPLYLIYPSVENVRTS LEGYPAGGSLPYSIQTAEKQNWLHS YFHKWSAETSGRSNAMPHIKTYMRP SPDFSKIAWFLVTSANLSKAAWGAL EKNGTQLMIRSYELGVLFLPSAFGL DSFKVKQKFFAGSQEPMATFPVPYD LPPELYGSKDRPWIWNIPYVKAPDT HGNMWVPS
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: TDP1 tyrosyl-DNA phosphodiesterase 1 [ Homo sapiens ]
• Official Symbol: TDP1
• Synonyms: TDP1; tyrosyl-DNA phosphodiesterase 1; FLJ11090; SCAN1; tyr-DNA phosphodiesterase 1; MGC104252
• Gene ID: 55775
• mRNA Refseq: NM_001008744
• Protein Refseq: NP_001008744
• MIM: 607198
• UniProt ID: Q9NUW8

Reviews

07/14/2022

Very professional customer service, fully understanding the needs of the customer and giving professional advice.

06/21/2021

The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

05/09/2021

Fast and timely shipment helped me to get satisfactory experimental results in short time.

Q&As

What are the effects of inhibiting TDP1 expression?

Inhibition of TDP1 expression induces apoptosis in gastric cancer cells.

What diseases has TDP1 been closely associated with the study of?

TDP1 has been closely associated with the study of diseases such as gastric cancer and lung cancer.

How does the expression level of TDP1 change in lung adenocarcinoma tissues?

Lung adenocarcinoma tissues expressed higher levels of TDP1 compared to paraneoplastic and normal tissues.

What is the biological function of TDP1?

TDP1 is involved in DNA damage repair and plays a driving role in tumorigenesis and development.