Recombinant Mouse Acadm Protein (Lys26-Asn421), C-His tagged

• Cat.No.: Acadm-5595M
• Product Overview: Recombinant mouse Acadm (Lys26-Asn421) fused with the C-terminal His tag was expressed in E. coli.

Specification

• Source: E. coli
• Species: Mouse
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 44.78 kDa
• Protein Length: Lys26-Asn421
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Acadm acyl-Coenzyme A dehydrogenase, medium chain [ Mus musculus (house mouse) ]
• Official Symbol: Acadm
• Synonyms: ACADM; acyl-Coenzyme A dehydrogenase, medium chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD; AU018656
• Gene ID: 11364
• mRNA Refseq: NM_007382
• Protein Refseq: NP_031408
• UniProt ID: P45952

Reviews

04/29/2022

Demonstrates excellent stability and consistency in long-term storage.

05/25/2018

Highly effective in detecting post-translational modifications of the target protein.

Q&As

How does the activity of this protein contribute to cellular metabolism?

The activity of acyl-CoA dehydrogenase medium chain contributes to the breakdown of medium-chain fatty acids to produce energy in cells.

Are there any known inhibitors or activators of this protein?

There are currently no known inhibitors or activators of acyl-CoA dehydrogenase medium chain protein.

What research is currently being conducted to further understand the function of acyl-CoA dehydrogenase medium chain protein?

Research is ongoing to further understand the function and regulation of acyl-CoA dehydrogenase medium chain protein, as well as its role in metabolic disorders.

What diseases or disorders are associated with mutations in this protein?

Mutations in this protein are associated with a variety of metabolic disorders, including medium-chain acyl-CoA dehydrogenase deficiency.

How is the expression of acyl-CoA dehydrogenase medium chain regulated?

The expression of acyl-CoA dehydrogenase medium chain is regulated by a variety of factors, including gene expression and protein degradation pathways.

Where is acyl-CoA dehydrogenase medium chain protein located within the cell?

Acyl-CoA dehydrogenase medium chain protein is located in the mitochondrial matrix.

What is the substrate specificity of this protein?

Acyl-CoA dehydrogenase medium chain protein has specificity for medium-chain fatty acyl-CoA substrates.

What is the structure of this protein and how does it relate to its function?

Acyl-CoA dehydrogenase medium chain protein has a flavin adenine dinucleotide (FAD)-binding domain that is essential for its function.

What is the function of acyl-CoA dehydrogenase medium chain protein?

Acyl-CoA dehydrogenase medium chain protein catalyzes the first step in the 尾-oxidation of medium-chain fatty acids.

What are the physiological roles of acyl-CoA dehydrogenase medium chain?

Acyl-CoA dehydrogenase medium chain plays a key role in energy metabolism and fatty acid oxidation in cells.