Recombinant Mouse ALKBH4 Protein Pre-coupled Magnetic Beads

• Cat.No.: ALKBH4-476M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Alkbh4 alkB, alkylation repair homolog 4 (E. coli) [ Mus musculus ]
• Official Symbol: ALKBH4
• Gene ID: 72041
• mRNA Refseq: NM_028070.1
• Protein Refseq: NP_082346.1
• UniProt ID: Q9D8F1

Reviews

03/15/2022

The protein has low cytotoxicity.

07/26/2020

Short half-life and high clearance rate.

02/09/2020

The stability of this protein is relatively good, heat resistance, acid and alkaline resistance and protease degradation test results are very good.

04/21/2019

This protein performed well by testing kinetic parameters such as enzymatic reaction rate, binding affinity and so on.

Q&As

Does ALKBH4 protein play a role in cardiovascular disease?

Current studies have shown that ALKBH4 protein may also play a role in cardiovascular disease.

Is ALKBH4 involved in DNA repair?

At present, it is believed that ALKBH4 protein is related to RNA repair, and its correlation with DNA repair needs to be further confirmed.

In what human diseases does the ALKBH4 protein play a role?

Current studies have found that ALKBH4 protein is related to a variety of cancers, intracranial hemorrhage and other diseases.

What is the biosynthesis mechanism of ALKBH4 protein?

The ALKBH4 protein is transcribed by the ALKBH4 gene and then translated into a protein.

Is the expression of ALKBH4 protein related to the occurrence and development of tumor?

Many studies have shown that the abnormal expression of ALKBH4 protein is related to the occurrence and development of some tumors.

Is ALKBH4 involved in post-translational modification?

There is no clear evidence that ALKBH4 protein is involved in the process of post-translational modification.

Does ALKBH4 protein interact with other genes?

ALKBH4 protein is known to interact with a variety of genes, including other RNA modifying enzymes and DNA damage response genes.

What is the main function of ALKBH4 protein?

ALKBH4 protein is mainly involved in RNA modification and regulation of gene expression.

What are the characteristics of ALKBH4 gene expression pattern?

The expression level of ALKBH4 gene is different in different tissues, and it may be regulated by exogenous factors.

Does ALKBH4 protein participate in cell apoptosis?

The relationship between ALKBH4 protein and apoptosis has not been confirmed.

What are the structural characteristics of ALKBH4 protein?

The structure of ALKBH4 protein is mainly characterized by the presence of methionine modification enzyme active center, which can assist RNA modification.

What chemical exposure is associated with ALKBH4 protein expression?

Current studies suggest that the expression of ALKBH4 protein is affected by environmental factors, including alkylating agents and oxidants.

What are the target molecules of ALKBH4 protein modification?

ALKBH4 protein mainly modifies RNA molecules such as tRNA and rRNA.

What is the application prospect of ALKBH4 protein in cancer treatment?

The ALKBH4 protein has become an important target for some cancer treatments, including drug therapies targeting the protein.