Recombinant Mouse ALOX12E Protein Pre-coupled Magnetic Beads
Cat.No. : | ALOX12E-482M-B |
Product Overview : | The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations. |
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Source : | HEK293 |
Species : | Mouse |
Form : | Solution |
Particle size : | ~2 μm |
Beads Surface : | Hydrophilic |
Capacity : | > 200 pmol rabbit IgG/ mg beads |
Applications : | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. |
Storage : | 2-8℃. Do not to freeze thaw the Beads |
Concentration : | 10mg beads/mL |
Storage Buffer : | PBS buffer |
Gene Name : | Alox12e arachidonate lipoxygenase, epidermal [ Mus musculus ] |
Official Symbol : | ALOX12E |
Gene ID : | 11685 |
mRNA Refseq : | NM_145684.1 |
Protein Refseq : | NP_663717.1 |
UniProt ID : | P55249 |
Products Types
◆ Recombinant Protein | ||
ALOX12E-291R | Recombinant Rat ALOX12E Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX12E-482M | Recombinant Mouse ALOX12E Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX12E-1565M | Recombinant Mouse ALOX12E Protein | +Inquiry |
ALOX12E-635R | Recombinant Rat ALOX12E Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (15)
Ask a questionThe detection methods of ALOX12E include immunohistochemistry, real-time fluorescence quantitative PCR, etc.
ALOX12E may be involved in the regulation of the effects of estrogen on the skin, but the specific role needs to be studied.
ALOX12E catalyzes the oxidation of arachidonic acid in epidermal cells to form 12-hydroxyarachidonic acid, thus participating in the keratinization process and skin barrier formation.
Overexpression of ALOX12E is associated with psoriasis, atopic dermatitis, and lupus erythematosus.
This protein may be involved in the regulation of skin immune response, but its specific role needs further study.
The gene for ALOX12E is located on human chromosome 17.
Point mutations in ALOX12E can lead to skin disorders such as abnormal keratosis and ichthyosis.
It may be activated in response to cell stimulation, such as trauma.
Inhibitors of ALOX12E include arabidopsis, procainamide, etc.
The ALOX12E signaling pathway is mainly realized through the MAPK signaling pathway.
ALOX12E may play an anti-apoptotic role in cell apoptosis.
ALOX12E has been linked to skin cancer, and its inhibitors can be used to treat skin cancer.
Abnormalities in ALOX12E have been linked to conditions such as psoriasis, atopic dermatitis and dry skin.
ALOX12E is mainly expressed in the skin and cornea.
The expression of ALOX12E is affected by many factors such as extracellular calcium ion concentration, extracellular oxygen partial pressure, and cytokines.
Customer Reviews (3)
Write a reviewWhen desensitize specific allergens, ALOX12E has a strong potential.
ALOX12E showed good compatibility and stability with various excipients.
The pharmacodynamic parameters of ALOX12E were better.
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