Recombinant Mouse ARX Protein, His (Fc)-Avi-tagged
Cat.No. : | ARX-767M |
Product Overview : | Recombinant Mouse ARX with His (Fc)-Avi tag was expressed and purified |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His (Fc)-Avi |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | ≥85% by SDS-PAGE |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | PBS buffer |
Gene Name : | Arx aristaless related homeobox [ Mus musculus ] |
Official Symbol : | ARX |
Gene ID : | 11878 |
mRNA Refseq : | NM_007492.3 |
Protein Refseq : | NP_031518.2 |
UniProt ID : | O35085 |
Products Types
◆ Recombinant Protein | ||
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ARX-468R | Recombinant Rat ARX Protein, His (Fc)-Avi-tagged | +Inquiry |
Arx-652M | Recombinant Mouse Arx Protein, MYC/DDK-tagged | +Inquiry |
ARX-2820H | Recombinant Human ARX Protein, MYC/DDK-tagged | +Inquiry |
ARX-812R | Recombinant Rat ARX Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (8)
Ask a questionMutations in the ARX gene disrupt normal brain development, leading to impaired neuronal migration, abnormal cortical structures, and cognitive and motor impairments.
Yes, the ARX protein contains a DNA-binding domain called the homeobox domain, allowing it to bind to specific DNA sequences and regulate gene transcription.
Yes, mutations in the ARX gene are associated with a higher risk of epilepsy, particularly West syndrome, a specific type of early-onset epilepsy.
Yes, mutations or alterations in ARX gene expression can result in intellectual disabilities, ranging from mild to severe, depending on the type of mutation and its impact on brain development.
Yes, the ARX protein also plays a role in the development of other organs, including the pancreas, testes, and skeletal muscles.
Yes, the ARX protein interacts with various co-factors, transcriptional regulators, and chromatin remodeling proteins to regulate gene expression during brain development.
Yes, mutations in the ARX gene are associated with a range of neurological disorders, such as X-linked lissencephaly with abnormal genitalia (XLAG), Partington syndrome, and West syndrome.
Yes, the ARX protein is involved in the development and function of the pancreas, where it regulates the production of insulin and glucagon, hormones involved in blood sugar regulation.
Customer Reviews (3)
Write a reviewThis protein has proven to be of great utility in protein electron microscopy structure analysis.
I highly recommend the ARX Protein to fellow researchers seeking a high-quality protein that not only meets their experimental requirements but is also accompanied by exceptional technical support.
The ARX Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.
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