Recombinant Mouse Atxn1, His-tagged
Cat.No. : | Atxn1-3684M |
Product Overview : | Ataxin-1 (Atxn1) |
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- Gene Information
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Source : | E. Coli or Yeast |
Species : | Mouse |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 791 |
Purity : | >90% |
Notes : | Small volumes of Atxn1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | Atxn1 ataxin 1 [ Mus musculus ] |
Official Symbol : | Atxn1 |
Synonyms : | ATXN1; ataxin 1; ataxin-1; spinocerebellar ataxia 1 homolog; Atx1; Sca1; C85907; Gm10786; 2900016G23Rik; ENSMUSG00000074917; |
Gene ID : | 20238 |
mRNA Refseq : | NM_001199304 |
Protein Refseq : | NP_001186233 |
Chromosome Location : | 13 A5; 13 21.98 cM |
Pathway : | mRNA processing, organism-specific biosystem; |
Function : | DNA binding; RNA binding; binding; identical protein binding; poly(G) RNA binding; poly(U) RNA binding; protein C-terminus binding; protein binding; protein self-association; |
Products Types
◆ Recombinant Protein | ||
ATXN1-409H | Recombinant Human ATXN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN1-556R | Recombinant Rat ATXN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN1-899M | Recombinant Mouse ATXN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Atxn1-1782M | Recombinant Mouse Atxn1 Protein, Myc/DDK-tagged | +Inquiry |
ATXN1-163H | Recombinant Human ATXN1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
ATXN1-8566HCL | Recombinant Human ATXN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionSCA1 is caused by mutations in the ATXN1 gene. The mutation resulted in the expansion of glutamine repeats in ATXN1 protein, resulting in the formation of abnormal polyglutamic acid protein. This protein abnormality can lead to abnormal neuronal function and degenerative changes, leading to the occurrence of SCA1.
Yes, the ATXN1 protein interacts with multiple proteins to form complexes involved in the regulation of a variety of cellular functions. For example, ATXN1 interacts with the Capicua (CIC) protein and is involved in transcriptional regulation.
The protein is associated with spinocerebellar ataxia type 1 (SCA1). SCA1 is an inherited neurodegenerative disease characterized by dysfunction of the cerebellum and spinal cord, leading to ataxia and other neurological symptoms.
ATXN1 protein is expressed in several tissues, but its expression is higher in the central nervous system, especially in the cerebellum and spinal cord.
The function of ATXN1 protein is regulated by a variety of regulatory mechanisms, including post-translational modification, assembly of protein complexes, and transcriptional regulation. These regulatory mechanisms ensure the adaptability and stability of ATXN1 protein.
ATXN1 protein is involved in the regulation of a variety of neural cell functions, including cell cycle regulation, DNA repair, transcription regulation, etc. It plays an important role in the development and functional maintenance of the nervous system.
Customer Reviews (3)
Write a reviewUsing Atxn1 as a catalyst, the rate and yield of chemical reactions can be significantly increased, and the catalytic efficiency is very high.
The stability of Atxn1 is very good, and its structure and function remain stable even after several freeze-thaw cycles, which shows its excellent quality control and production process.
Atxn1 are so simple to prepare that we can easily prepare them ourselves.
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