Recombinant Mouse Dnm1 protein, His & T7-tagged

• Cat.No.: Dnm1-2028M
• Product Overview: Recombinant Mouse Dnm1 aa. (Leu572~Ile745 (Accession # P39053)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.1kDa
• Protein length: Leu572~Ile745 (Accession # P39053)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Dnm1 dynamin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dnm1
• Synonyms: ABCB8; ATP binding cassette subfamily B member 8; MABC1; M-ABC1; EST328128; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; mitochondrial ABC protein; mitochondrial ATP-binding cassette 1
• Gene ID: 13429
• mRNA Refseq: NM_001301737.1
• Protein Refseq: NP_001288666.1
• UniProt ID: P39053

Reviews

09/06/2022

Precise protein quantification, ensures data accuracy in our experiments.

05/26/2021

Accurate mass spectrometry, essential for precise proteomics analysis.

03/06/2021

Efficient peptide synthesis, accelerates our peptide research efficiently.

Q&As

How does DNM1 contribute to the development and maintenance of neural networks?

DNM1 contributes to the formation and maintenance of neural circuits, essential for brain function.

What role does DNM1 play in endocytosis and membrane trafficking within cells?

DNM1 plays a key role in endocytosis, facilitating membrane trafficking and cellular transport processes.

What are the mechanisms by which DNM1 modulates synaptic plasticity and learning?

DNM1 regulates synaptic plasticity, crucial for learning and memory formation.

How do alterations in DNM1 expression or function affect neurodegenerative diseases?

Changes in DNM1 function can influence the progression of neurodegenerative diseases, affecting neuronal health and connectivity.

How does DNM1 (Dynamin 1) regulate synaptic vesicle recycling and neurotransmitter release in neurons?

DNM1 is crucial for synaptic vesicle recycling, controlling neurotransmitter release at synapses.

How does DNM1 influence cellular signaling pathways, particularly in the nervous system?

DNM1 impacts cellular signaling in neurons, influencing various neuronal activities and responses.

What is the impact of DNM1 mutations on neurological disorders, such as epilepsy?

Mutations in DNM1 are linked to neurological conditions like epilepsy, affecting synaptic function.