Recombinant Mouse Rchy1 Protein, Myc/DDK-tagged
Cat.No. : | Rchy1-5437M |
Product Overview : | Purified recombinant protein of mouse full-length ring finger and CHY zinc finger domain containing 1 (Rchy1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | This gene encodes a protein containing CHY-, CTCHY-, and RING-type zinc-fingers. The encoded protein functions as an E3 ubiquitin ligase, and mediates the degradation of target proteins such as p53. The activity of this protein is important in cell cycle regulation. Alternative splicing results in multiple transcript variants. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 30 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rchy1 ring finger and CHY zinc finger domain containing 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Rchy1 |
Synonyms : | RCHY1; ring finger and CHY zinc finger domain containing 1; RING finger and CHY zinc finger domain-containing protein 1; zinc finger protein 363; E3 ubiquitin-protein ligase Pirh2; CH-rich-interacting match with PLAG1; androgen receptor N-terminal-interacting protein; ARNIP; CHIMP; Pirh2; Zfp363; mARNIP; PRO1996; AU042618; 6720407C15Rik |
Gene ID : | 68098 |
mRNA Refseq : | NM_026557 |
Protein Refseq : | NP_080833 |
UniProt ID : | Q9CR50 |
Products Types
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RCHY1-234H | Recombinant Human RCHY1 Protein, Myc/DDK-tagged | +Inquiry |
RCHY1-11879Z | Recombinant Zebrafish RCHY1 | +Inquiry |
RCHY1-3643C | Recombinant Chicken RCHY1 | +Inquiry |
◆ Lysates | ||
RCHY1-2444HCL | Recombinant Human RCHY1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionRCHY1 acts as an independent target in early-stage node-negative oral squamous cell carcinoma and may provide patients with more accurate diagnostic and prognostic information.
The association between RCHY1 and ovarian and breast cancer is mainly manifested in its regulation of hormone receptor expression, migration and invasion.
RCHY1, as a Ubiquitin ligase, has been found as a driving factor in a variety of cancers such as liver, prostate, and kidney cancer.
RCHY1 is expressed in different types of cancer, and its high expression is associated with poor prognosis and high risk of metastasis.
For breast and ovarian cancer patients, the polymorphisms of RCHY1 are associated with the risk of tumor recurrence and can be used as a biomarker to predict recurrence.
RCHY1 is involved in regulating apoptosis signaling pathways by mediating the single ubiquitination pathway and promoting apoptosis of tumor cells.
Customer Reviews (3)
Write a reviewExperiments using RCHY1 were very reproducible and allowed me to evaluate the results more accurately.
Due to stability of RCHY1 was still very good under different experimental conditions, indicating that it has a wide range of applications and adaptability.
The band definition of RCHY1 in Western blot was very high, which improved the confidence of the experiment.
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