Recombinant Mouse Zap70 protein, His & T7-tagged
Cat.No. : | Zap70-1491M |
Product Overview : | Recombinant Mouse Zap70 aa. (Ala270~Pro560 (Accession # P43404)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the protein tyrosine kinase family. The encoded protein is essential for development of T lymphocytes and thymocytes, and functions in the initial step of T lymphocyte receptor-mediated signal transduction. A mutation in this gene causes chronic autoimmune arthritis, similar to rheumatoid arthritis in humans. Mice lacking this gene are deficient in alpha-beta T lymphocytes in the thymus. In humans, mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T lymphocytes. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Mouse |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 37.0kDa |
Protein length : | Ala270~Pro560 (Accession # P43404) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 9.1 |
Gene Name : | Zap70 zeta-chain (TCR) associated protein kinase [ Mus musculus (house mouse) ] |
Official Symbol : | Zap70 |
Synonyms : | Zap70; zeta-chain (TCR) associated protein kinase; Srk; mur; mrtle; ZAP-70; tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; syk-related tyrosine kinase |
Gene ID : | 22637 |
mRNA Refseq : | NM_001289612.1 |
Protein Refseq : | NP_001276541.1 |
UniProt ID : | P43404 |
Products Types
◆ Recombinant Protein | ||
Zap70-7046M | Recombinant Mouse Zap70 Protein, Myc/DDK-tagged | +Inquiry |
ZAP70-2382H | Recombinant Human ZAP70 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZAP70-10274M | Recombinant Mouse ZAP70 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZAP70-1511H | Active Recombinant Human ZAP70 Protein, GST-tagged | +Inquiry |
ZAP70-98H | Recombinant Human Zeta-chain (TCR) Associated Protein Kinase 70kDa | +Inquiry |
◆ Lysates | ||
ZAP70-1948HCL | Recombinant Human ZAP70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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