Recombinant Pan troglodytes (Chimpanzee) ASAH1, His-tagged
Cat.No. : | ASAH1-3066P |
Product Overview : | Acid ceramidase (ASAH1) |
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Source : | E. Coli or Yeast |
Species : | Pan troglodytes (Chimpanzee) |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 395 |
Purity : | >90% |
Notes : | Small volumes of ASAH1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 [ Pan troglodytes ] |
Official Symbol : | ASAH1 |
Synonyms : | AC; acid ceramidase; ACDase; acid Cdase; Acylsphingosine deacylase; N-acylsphingosine amidohydrolase 1 |
Gene ID : | 464022 |
mRNA Refseq : | NM_001098560 |
Protein Refseq : | NP_001092030 |
UniProt ID : | A5A6P2 |
Chromosome Location : | chromosome: 8 |
Pathway : | Lysosome, organism-specific biosystem; Lysosome, conserved biosystem |
Products Types
◆ Recombinant Protein | ||
Asah1-655M | Recombinant Mouse Asah1 Protein, MYC/DDK-tagged | +Inquiry |
ASAH1-470R | Recombinant Rat ASAH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASAH1-524H | Recombinant Human ASAH1 Protein, His-tagged | +Inquiry |
ASAH1-2093M | Recombinant Mouse ASAH1 Protein (19-141 aa), His-GST-Myc-tagged | +Inquiry |
ASAH1-65C | Recombinant Cynomolgus Monkey ASAH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ASAH1-8670HCL | Recombinant Human ASAH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (8)
Ask a questionGiven the involvement of ASAH1 in various diseases, including cancer, modulating its activity or developing ASAH1 inhibitors holds promise as potential therapeutic strategies.
Yes, alterations in ASAH1 gene expression or activity can impact cellular differentiation processes, as ceramide metabolism is crucial for normal development and tissue homeostasis.
Yes, mutations or deficiencies in the ASAH1 gene are associated with Farber disease, a rare inherited disorder characterized by the accumulation of ceramide in tissues throughout the body.
ASAH1 deficiency, as seen in Farber disease, is a genetic disorder. Prevention involves genetic counseling for at-risk individuals and prenatal testing during pregnancy.
Currently, ASAH1 deficiency is not included in routine newborn screening panels. However, advancements in testing methods may lead to its inclusion in the future.
Besides its role in ceramide metabolism, the ASAH1 protein can affect immune response, inflammation, and cellular stress responses.
Dysfunction of the ASAH1 protein impairs the breakdown of ceramide, leading to its accumulation in various tissues and disrupting cellular homeostasis.
Yes, the ASAH1 protein can modulate signaling pathways like the sphingosine-1-phosphate pathway, which influences various cellular processes such as migration, inflammation, and angiogenesis.
Customer Reviews (3)
Write a reviewSuch dedicated support makes me feel confident in my choice of using the ASAH1 protein for my experiments.
The manufacturer's commitment to excellence is truly commendable, especially when it comes to their outstanding technical support.
The ASAH1 Protein is a protein of exceptional quality that surpasses my expectations and fulfills all my experimental requirements.
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