Recombinant Rat ACAA1B Protein Pre-coupled Magnetic Beads

• Cat.No.: ACAA1B-88R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rat
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Acaa1b acetyl-Coenzyme A acyltransferase 1B [ Rattus norvegicus ]
• Official Symbol: ACAA1B
• Gene ID: 501072
• mRNA Refseq: NM_001040019.1
• Protein Refseq: NP_001035108.1
• UniProt ID: P07871

Reviews

03/30/2022

Shows good stability and compatibility with various sample types and buffers.

09/05/2021

Demonstrates excellent specificity and sensitivity in detecting the target protein in sandwich ELISAs.

05/02/2016

Highly efficient in neutralizing the activity of the target protein in bioassays.

Q&As

What is the structure of the acetyl-Coenzyme A acyltransferase 1B protein?

The acetyl-Coenzyme A acyltransferase 1B protein structure is composed of an N-terminal domain, a central domain, and a C-terminal domain.

What is the tissue distribution of acetyl-Coenzyme A acyltransferase 1B expression?

Acetyl-Coenzyme A acyltransferase 1B is mainly expressed in liver and adipose tissue, but also in other tissues such as muscle and brain.

How is acetyl-Coenzyme A acyltransferase 1B involved in insulin sensitivity and diabetes?

Acetyl-Coenzyme A acyltransferase 1B is involved in regulating insulin sensitivity and glucose homeostasis, and dysregulation of this protein has been implicated in the development of diabetes.

How is acetyl-Coenzyme A acyltransferase 1B regulated?

Acetyl-Coenzyme A acyltransferase 1B is regulated by post-translational modifications, transcriptional regulation, and by various signaling pathways.

What is the role of acetyl-Coenzyme A acyltransferase 1B in lipid metabolism?

Acetyl-Coenzyme A acyltransferase 1B plays a key role in lipid metabolism by catalyzing the conversion of acetyl-CoA and fatty acid CoA thioesters to produce long-chain acyl-CoAs, which are then used for energy production or storage.

What are the substrates of acetyl-Coenzyme A acyltransferase 1B?

The substrates of acetyl-Coenzyme A acyltransferase 1B are acetyl-CoA and fatty acid CoA thioesters.

What diseases are associated with mutations in the acetyl-Coenzyme A acyltransferase 1B gene?

Mutations in the acetyl-Coenzyme A acyltransferase 1B gene have been associated with metabolic disorders such as obesity and insulin resistance.

What is the relationship between acetyl-Coenzyme A acyltransferase 1B and fatty acid synthesis?

Acetyl-Coenzyme A acyltransferase 1B is not directly involved in fatty acid synthesis, but it plays a role in the regulation of fatty acid metabolism and the synthesis of complex lipids.

What is the function of acetyl-Coenzyme A acyltransferase 1B protein?

The function of acetyl-Coenzyme A acyltransferase 1B protein is to catalyze the conversion of acetyl-CoA and fatty acid CoA thioesters to produce long-chain acyl-CoAs.

What is the evolutionary history of the acetyl-Coenzyme A acyltransferase 1B gene and protein?

The acetyl-Coenzyme A acyltransferase 1B gene and protein are conserved throughout evolution and are found in a wide range of organisms, from bacteria to humans.