Recombinant Rat SEMA6B Protein Pre-coupled Magnetic Beads

• Cat.No.: SEMA6B-4974R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rat
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Sema6b sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B [ Rattus norvegicus ]
• Official Symbol: SEMA6B
• Gene ID: 84609
• mRNA Refseq: NM_053471.2
• Protein Refseq: NP_445923.1
• UniProt ID: O70141

Reviews

01/08/2022

The manufacturer offers a wide range of SEMA6B protein variants, including recombinant or native forms, as well as different conjugates and modifications.

04/26/2021

As a researcher using SEMA6B protein, I have found numerous advantages in its application during trials for various experimental purposes.

05/13/2017

The SEMA6B protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.

Q&As

In which cancers is SEMA6B expression implicated?

SEMA6B has been associated with various cancers, including breast, lung, and prostate cancer, indicating its potential role in tumor progression.

How is SEMA6B expression regulated in normal physiological conditions?

The expression of SEMA6B is tightly regulated at the transcriptional and post-translational levels to ensure proper cellular functions.

Can SEMA6B be a potential therapeutic target?

Research suggests that targeting SEMA6B may have therapeutic implications, especially in conditions where axon guidance plays a role.

Are there any diseases associated with SEMA6B dysregulation?

Yes, altered expression of SEMA6B has been linked to certain neurological disorders and cancers.

How does SEMA6B contribute to axon guidance?

SEMA6B acts as a guidance cue for developing axons, influencing their growth and navigation during neural development.