Recombinant Swine IL15
Cat.No. : | IL15-263S |
Product Overview : | Swine IL-15 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
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Description : | Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 was discovered to be a member of a family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-21. The specific receptor for IL-15, IL-15 receptor alpha, appears to regulate IL-15 secretion, stability, and activity. All members of this family use the common gamma chain as part of their signaling complex. IL-15 has been shown to play a role in many diseases, including obesity, influenza, and inflammatory autoimmune diseases. |
Source : | Yeast |
Species : | Swine |
Form : | Lyophilized without carrier protein. |
Molecular Mass : | Swine IL-15 has a predicted molecular weight of 13.1 kDa. |
AA Sequence : | TWQHVISDLK KIEDLIRSIH MDATLYTESD AHPNCKVTAM KCFLLELRVI LQESRNSDIS DTVENLIILA NSSLSSIEYK TESGCKECEE LEEKNINEFL KSFIHIVQMF INPS (114) |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Applications : | The Swine IL-15 protein can be used in cell culture, as an IL-15 ELISA Standard, and as a Western Blot Control. |
Storage : | Stable for up to twelve months from date of receipt at -20ºC. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20ºC. Avoid repeated freeze/thaw cycles. |
Reconstitution : | Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Gene Name : | IL15 interleukin 15 [ Sus scrofa (pig) ] |
Official Symbol : | IL15 |
Synonyms : | IL15; interleukin 15; IL-15; interleukin-15 |
Gene ID : | 397683 |
mRNA Refseq : | NM_214390 |
Protein Refseq : | NP_999555 |
UniProt ID : | Q95253 |
Chromosome Location : | 8; 8 |
Pathway : | Cytokine-cytokine receptor interaction; HTLV-I infection; HTLV-I infection |
Function : | cytokine activity; cytokine receptor binding |
Products Types
◆ Recombinant Protein | ||
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Il15-50M | Active Recombinant Mouse Il15 Protein (Asn49-Ser162), N-His tagged, Animal-free, Carrier-free | +Inquiry |
IL15-507H | Recombinant Human IL15 Protein | +Inquiry |
◆ Lysates | ||
IL15-5248HCL | Recombinant Human IL15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionTechniques discern IL15 and IL2 receptor binding kinetics.
Methods explore IL15's role in autoimmune disease mechanisms.
IL15 knockout models provide insights into its diverse functions.
IL15's influence on memory T cell differentiation investigated.
Immunofluorescence microscopy visualizes IL15 subcellular localization.
Approaches validate IL15's involvement in inflammatory responses.
IL15's role in NK cell cytotoxicity analyzed using assays.
ELISA measures IL15 secretion accurately.
qPCR quantifies IL15's impact on regulatory T cells.
Flow cytometry quantifies IL15-driven T-cell proliferation.
Customer Reviews (3)
Write a reviewMapping protein- interactions in DNA transcription for gene regulation.
Suitable for cytotoxicity assays.
Effective in NK cell activation.
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