Recombinant Zebrafish ARHGEF18A

• Cat.No.: ARHGEF18A-12827Z
• Product Overview: Recombinant Zebrafish ARHGEF18A full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: arhgef18a rho/rac guanine nucleotide exchange factor (GEF) 18a [ Danio rerio (zebrafish) ]
• Official Symbol: ARHGEF18A
• Gene ID: 407987
• mRNA Refseq: NM_214818
• Protein Refseq: NP_999983
• UniProt ID: Q6NSP2

Reviews

02/08/2023

It can be seamlessly integrated into various molecular biology techniques, such as immunoassays, cell-based functional assays, and protein-protein interaction studies.

11/13/2022

Its adaptability enables researchers to unravel the complex interplay and functional relevance of ARHGEF18A in different biological processes.

04/16/2021

They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.

04/13/2021

the manufacturer's technical support is instrumental in assisting researchers throughout their trials.

07/29/2019

The prompt and precise support provided by the manufacturer ensures that researchers can proceed with their work smoothly, without any hindrances or uncertainties.

07/28/2018

They can provide valuable guidance in experimental design, optimization, and troubleshooting, helping researchers overcome challenges and maximize the efficiency of their trials.

06/02/2017

The manufacturer's technical support can also aid researchers in the data analysis phase.

09/25/2016

As a researcher utilizing the ARHGEF18A protein in my trials, I have been highly impressed with its numerous advantages that significantly contribute to the success of my experimental endeavors.

Q&As

Can ARHGEF18A be targeted for therapeutic interventions?

As of now, there are no known therapeutic interventions directly targeting ARHGEF18A. However, if its involvement in specific diseases or conditions is further elucidated, it might become a potential target for therapeutic development in the future.

Are there any animal models available to study the function of ARHGEF18A?

Due to limited research on ARHGEF18A, there are no specific animal models designed to study its function. However, animal models with genetic modifications in the ARHGEF18A gene could be generated to better understand its role in various biological processes.

What role does ARHGEF18A play in neurodevelopmental disorders?

While ARHGEF18A is not as extensively linked to neurodevelopmental disorders as its variant counterpart ARHGEF18, further research is needed to determine its specific involvement in conditions like autism spectrum disorder or intellectual disability.

Are there any known interactions between ARHGEF18A and other proteins?

Yes, ARHGEF18A can interact with various proteins to mediate its functions. These interactions may involve binding to other guanine nucleotide exchange factors, Rho GTPases, or proteins involved in cytoskeletal dynamics, cell signaling, or other cellular processes.

Are there any known disease-associated mutations in the ARHGEF18A gene?

Currently, there is limited information available regarding disease-associated mutations in the ARHGEF18A gene. Further studies and genetic analyses are necessary to determine if any mutations in ARHGEF18A are linked to specific disorders or conditions.

Is ARHGEF18A protein expressed in all cell types?

The expression of ARHGEF18A might be cell-type specific, with varying levels in different tissues and cell types. Further studies are needed to determine its expression pattern across various cell types and tissues.