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DLK1

  • Official Full Name

    delta-like 1 homolog

  • Overview

    DLK1 (delta-like-1), also known as fetal antigen 1 (FA1) and preadipocyte factor 1 (pref-1), is a member of the epidermal growth factor (EGF)-like family of proteins, containing six tandem EGF-like repeats. DLK1 is a paternally expressed, imprinted gene t
  • Synonyms

    DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; Delta1; FA1; pG2; Pref 1; ZOG; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1; DLK; PREF1; Pref-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • Myc
  • GST
  • hFc
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DLK1-195H Active Recombinant Human DLK1, His-tagged Mammalian cells His
Human DLK1-187H Recombinant Human DLK1 protein, His-tagged Insect Cell His
Human DLK1-26914TH Recombinant Human DLK1, Fc-tagged HEK293 Fc 303 amino acids
Human DLK1-2683H Recombinant Human DLK1 Protein, GST-tagged Wheat Germ GST
Human DLK1-2079H Recombinant Human Delta-like 1 Homolog (Drosophila), FLAG-tagged HEK293 Flag
Human DLK1-528H Recombinant Human DLK1 Protein HEK293 N/A
Human DLK1-26164TH Recombinant Human DLK1, FLAG-tagged HEK293 Flag 303 amino acids
Human DLK1-12023H Recombinant Human DLK1, GST-tagged E.coli GST 83-383a.a.
Human DLK1-188H Recombinant Human DLK1 protein, His-tagged HEK293 His Ala24-Pro297
Human DLK1-6909HCL Recombinant Human DLK1 293 Cell Lysate HEK293 N/A
Human DLK1-2801H Recombinant Human DLK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DLK1-001H Recombinant Human DLK1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human DLK1-1839H Recombinant Human DLK1 protein, His-tagged E.coli His Asn177~Phe326 (Accession # P80370)
Human DLK1-5007H Recombinant Human DLK1 protein, Flag-Myc-tagged HEK293 Flag-Myc 24-303aa
Human DLK1-583H Active Recombinant Human DLK1 protein, hFc-tagged HEK293 hFc Ala24-Gln303
Human DLK1-5391H Recombinant Human DLK1 protein, His-tagged Yeast His 24-303aa
Human DLK1-2820H Recombinant Human DLK1 protein, His-tagged E.coli His 24-303aa
Human DLK1-1347H Recombinant Human DLK1 Protein, His&GST-tagged E.coli N-His&GST Ser206-Pro366
Human DLK1-3992HF Recombinant Full Length Human DLK1 Protein, GST-tagged In Vitro Cell Free System GST 25-383 amino acids
Human DLK1-189H Active Recombinant Human DLK1 protein, His-tagged HEK293 His Ala 24 - Gly 303
Human DLK1-3124H Recombinant Human DLK1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DLK1-2801H-B Recombinant Human DLK1 Protein Pre-coupled Magnetic Beads HEK293
Human DLK1-2262H Recombinant Human DLK1 Protein (Ala24-Pro297), C-His tagged Mammalian cells C-His Ala24-Pro297
Mouse Dlk1-216M Active Recombinant Mouse Dlk1 protein, His-tagged Mammalian cells His Ala24-Gln305
Mouse Dlk1-2115M Recombinant Mouse Delta-like 1 Homolog (Drosophila), Fc Chimera HEK293 Fc
Mouse Dlk1-1840M Recombinant Mouse Dlk1 protein, His & GST-tagged E.coli His/GST Ala24~Ser175 (Accession # Q09163)
Mouse Dlk1-2400M-B Recombinant Mouse Dlk1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Dlk1-2579M Recombinant Mouse Dlk1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Dlk1-2400M Recombinant Mouse Dlk1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Dlk1-1841R Recombinant Rat Dlk1 protein, His & T7-tagged E.coli His/T7 Asp81~Gly311 (Accession # O70534)
Cynomolgus DLK1-1911C Active Recombinant Cynomolgus DLK1 protein, His-tagged HEK293 His Ala 24 - Cys 306
Chicken DLK1-3889C Recombinant Chicken DLK1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DLK1 Related Articles
  • DLK1 Related Research Area
  • DLK1 Related Signal Pathway

DLK1 involved in several pathways and played different roles in them. We selected most pathways DLK1 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Adipogenesis, FOXA2 and FOXA3 transcription factor networks, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activated NOTCH1 Transmits Signal to the NucleusDNER;DTX2;DLK1;ADAM10;MIB1;CNTN1;JAG1;JAG2
AdipogenesisCELF1;E2F4;PLIN2;CEBPD;CTNNB1;GADD45A;EGR2B;MEF2AA;NR2F1
FOXA2 and FOXA3 transcription factor networksUCP2;CPT1C;FOXF1;CPT1B;TTR;CEBPA;CPT1A;DLK1;KCNJ11
Notch signaling pathwayKAT2A;DNER;MAML1;HER6;DLB;SNW1;MIB1;ADAM17;RBPJA
Signal TransductionNMBB;OR10A5;RLN2;CCL35.2;PTH;FOXH1;NPB;SHB;USP9
Signaling by NOTCHRAB6A;MDK;MDKB;TLE3;MDKA;DTX2;TLE2;HEYL;DNER
Signaling by NOTCH1DNER;DTX2;HEYL;DLK1;TLE3

DLK1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DLK1 itself. We selected most functions DLK1 had, and list some proteins which have the same functions with DLK1. You can find most of the proteins on our site.

Function Related Protein
molecular_functionNPTX2;GPSM3;CREG2;NAIF1;TMEM56B;TMEM222A;PCDHGA4;PHF3;STPG1

DLK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLK1.

Ito, K; Yanagida, A; et al. Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts. LIVER INTERNATIONAL 34:1378-1390(2014).
Persson-Augner, D; Lee, YW; et al. Delta-Like 1 Homologue (DLK1) Protein in Neurons of the Arcuate Nucleus That Control Weight Homeostasis and Effect of Fasting on Hypothalamic DLK1 mRNA. NEUROENDOCRINOLOGY 100:209-220(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does DLK1 protein contribute to cell senescence? 11/12/2021

DLK1 has been found to play a role in cellular senescence, and understanding this process may have implications for aging-related research.

Are there ongoing clinical trials involving DLK1 protein? 04/20/2021

Yes, there are clinical trials exploring the therapeutic potential of targeting DLK1 in cancer treatment and regenerative medicine.

How is DLK1 protein linked to adipogenesis? 12/28/2020

DLK1 is involved in the regulation of adipocyte differentiation, and understanding its role may have implications for obesity-related research.

How does DLK1 protein impact stem cell differentiation? 12/08/2020

DLK1 is involved in the regulation of stem cell differentiation, making it a potential target for therapeutic applications in regenerative medicine.

Can manipulating DLK1 expression have therapeutic benefits? 05/21/2019

Modulating DLK1 expression holds promise for therapeutic interventions, such as controlling cell growth in cancer or enhancing tissue regeneration.

Customer Reviews (3)

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Reviews
10/14/2022

    In addition to these experimental benefits, the manufacturer of DLK1 protein plays a vital role in supporting researchers.

    06/15/2022

      DLK1 protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.

      01/24/2018

        DLK1 protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.

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