Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

FOXP2

  • Official Full Name

    forkhead box P2

  • Overview

    This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Synonyms

    FOXP2; forkhead box P2; SPCH1; CAGH44; TNRC10; forkhead box protein P2; CAG repeat protein 44; trinucleotide repeat containing 10; forkhead/winged-helix transcription factor; trinucleotide repeat-containing gene 10 protein;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FOXP2-12985H Recombinant Human FOXP2, His-tagged E.coli His 1-56a.a.
Human FOXP2-937H-B Recombinant Human FOXP2 Protein Pre-coupled Magnetic Beads HEK293
Human FOXP2-4473H Recombinant Human FOXP2 Protein, GST-tagged Wheat Germ GST
Human FOXP2-2558H Recombinant Human FOXP2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FOXP2-2849H Recombinant Human FOXP2 Protein (Ser488-Leu623), N-His tagged E.coli N-His Ser488-Leu623
Human FOXP2-4407H Recombinant Human FOXP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FOXP2-1523H Recombinant Human FOXP2 Protein, His&GST-tagged E.coli N-His&GST Met1-Ile244
Human FOXP2-30134H Recombinant Human FOXP2 protein, GST-tagged E.coli GST Met1-Gln56
Human FOXP2-5106HF Recombinant Full Length Human FOXP2 Protein, GST-tagged In Vitro Cell Free System GST 67 amino acids
Human FOXP2-1866HFL Recombinant Full Length Human FOXP2 Protein, C-Flag-tagged Mammalian cells Flag
Human FOXP2-937H Recombinant Human FOXP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FOXP2-6011M Recombinant Mouse FOXP2 Protein Mammalian Cell His
Mouse FOXP2-3338M Recombinant Mouse FOXP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Foxp2-507M Recombinant Mouse Foxp2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse FOXP2-3338M-B Recombinant Mouse FOXP2 Protein Pre-coupled Magnetic Beads HEK293
Rat FOXP2-2389R Recombinant Rat FOXP2 Protein Mammalian Cell His
Rat FOXP2-2045R-B Recombinant Rat FOXP2 Protein Pre-coupled Magnetic Beads HEK293
Rat FOXP2-2045R Recombinant Rat FOXP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FOXP2-1745R Recombinant Rhesus monkey FOXP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FOXP2-1567R-B Recombinant Rhesus Macaque FOXP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FOXP2-1567R Recombinant Rhesus Macaque FOXP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish FOXP2-3220Z Recombinant Zebrafish FOXP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FOXP2 Related Articles

FOXP2 involved in several pathways and played different roles in them. We selected most pathways FOXP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FOXP2 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXP2 itself. We selected most functions FOXP2 had, and list some proteins which have the same functions with FOXP2. You can find most of the proteins on our site.

Function Related Protein
DNA bindingDACH1;CR2;DMBX1A;PAX2B;ZNF446;DMRTA2;ZZZ3;DEK;ZBTB16
metal ion bindingMAP3K13;DNMT3L;MTMR3;ITGA7;ZNF625;DMRT3A;NKD2A;BCL11A;GALNS
protein bindingRCHY1;LIMA1;ATL2;GFOD1;IST1;COMMD3;C1QA;ATP1B2;IFT46
protein homodimerization activityACAT1;S100A13;AADAT;HNF4A;ACOT7;CARS;USH1G;BCL2A;C9orf142
sequence-specific DNA bindingFOXF2;VSX1;NR1H3;HOXC12;FOXK2;RX2;NR2E3;FOXP4;MAFG
transcription factor activity, sequence-specific DNA bindingCREB3L3A;HNF1A;NR1D1;ZKSCAN6;ZFP184;POU3F3B;TADA3;ZNF484;TSC22D1

FOXP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXP2.

arre2_element_mouse_il2_promoter; SDCBP; CCNC; CTBP2; AES; CTBP1; PIN1

Renier, N; Wu, ZH; et al. iDISCO: A Simple, RapidMethod to Immunolabel Large Tissue Samples for Volume Imaging. CELL 159:896-910(2014).
Iwai, L; Ohashi, Y; et al. FoxP2 is a Parvocellular-Specific Transcription Factor in the Visual Thalamus of Monkeys and Ferrets. CEREBRAL CORTEX 23:2204-2212(2013).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All FOXP2 Products

Required fields are marked with *

My Review for All FOXP2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends