ACAP2
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Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
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Overview
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the ACAP2 gene. -
Synonyms
ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2; centaurin, beta 2 , CENTB2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; CNT B2; KIAA0041; ACAP 2; Arf GAP with coiled coil ANK repeat and PH domains 2; CENT B 2; Centaurin beta2; CENTB 2; CENTB2; Cntb2; Similar to yeast ZINC FINGER PROTEIN GCS1; centaurin-beta-2; centaurin, beta 2; OTTHUMP00000208844; Arf GAP with coiled coil, ANK repeat and PH domains 2; CNT-B2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ACAP2 Related Articles
ACAP2 involved in several pathways and played different roles in them. We selected most pathways ACAP2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Endocytosis | ARAP1;USP8;CAPZA1B;SPG20A;KDRL;PIP5K1BB;RET;ARPC4L;RAB35 |
ACAP2 has several biochemical functions, for example, GTPase activator activity, Rab GTPase binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACAP2 itself. We selected most functions ACAP2 had, and list some proteins which have the same functions with ACAP2. You can find most of the proteins on our site.
Function | Related Protein |
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GTPase activator activity | TBC1D10C;USP6NL;ASAP1;ARFGAP3;RGS11;ARHGAP28;ARHGEF6;SMAP1;ARHGAP4 |
Rab GTPase binding | SYTL3;MICALL1;BICD1;PDE6D;RAB3GAP2;RAB11FIP1;NGFR;RAB11FIP4A;FER |
metal ion binding | ZNF563;ARSK;PDE6B;ZBTB5;GDPD2;ZNF256;DMRT3;GBGT1;ZSCAN4 |
ACAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACAP2.
HSPB1; pi3p; k1_vaccw; PDK3; Tgs1; Naa10
- Q&As
- Reviews
Q&As (10)
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Recombinant ACAP2 protein can be used for various applications, such as biochemical assays, protein-protein interaction studies, and drug discovery. It can also be used as an immunogen for antibody production or as a standard in ELISA assays.
Recombinant ACAP2 protein can be used in both in vitro and in vivo assays, depending on your research needs. In vitro assays can include biochemical assays, protein-protein interaction studies, and enzymatic assays, while in vivo assays can include cell-based assays or animal models.
ACAP2 is involved in the regulation of cytokinesis by controlling the activity of RhoA, a small GTPase that plays a critical role in the formation of the contractile ring. ACAP2 interacts with RhoA and regulates its activity, which is necessary for the proper formation and contraction of the contractile ring.
ACAP2 is involved in the regulation of clathrin-mediated endocytosis (CME) by controlling the formation of clathrin-coated vesicles. It interacts with multiple proteins such as AP2, Eps15, and dynamin, and regulates the activity of Arf6 GTPase, which is essential for the formation of clathrin-coated vesicles.
Creative BioMart offers customization or modification services for recombinant ACAP2 protein, such as adding tags or modifying the protein sequence.
It depends on the specific product. Generally, the price is based on factors such as purity, quantity, and functional activity. Please submit an inquiry form for specific products, or contact our technical support staff for consultation.
The presence or absence of post-translational modifications in recombinant ACAP2 protein can vary depending on the expression system and the purification method used. We support custom production of recombinant proteins, and you can describe your specific research requirements when submitting the online inquiry form.
ACAP2 is involved in the regulation of cell migration by controlling the activity of Rac1, a small GTPase that plays a critical role in the formation of lamellipodia and membrane ruffling. ACAP2 interacts with Rac1 and regulates its activity, which is necessary for the formation of these structures during cell migration.
ACAP2 has been shown to play a critical role in the regulation of cell proliferation and survival, and its dysregulation has been linked to the development and progression of various types of cancer. ACAP2 has been shown to be upregulated in several types of cancer, including breast, lung, and liver cancer, and its inhibition has been proposed as a potential therapeutic strategy for cancer treatment.
Customer Reviews (3)
Write a reviewI am very satisfied with the recombinant human ACAP2 protein. The product was of high quality and helped me achieve excellent results.
I have had nothing but positive experiences with Creative BioMart. Their recombinant ACAP2 proteins are consistently high-quality and their customer service is excellent.
Thanks to Creative BioMart's recombinant ACAP2 proteins, my research has progressed much more quickly than I had anticipated.
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