ADCK5
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Official Full Name
aarF domain containing kinase 5
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Synonyms
ADCK5; aarF domain containing kinase 5; uncharacterized aarF domain-containing protein kinase 5; FLJ35454; MGC126708;
- Recombinant Proteins
- Cell & Tissue Lysates
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- GST
- His
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ADCK5-326H | Recombinant Human ADCK5 Protein, GST-tagged | Wheat Germ | GST | ||
Human | ADCK5-98H | Recombinant Human ADCK5, GST-tagged | Sf9 Insect Cell | GST | ||
Human | ADCK5-9407H | Recombinant Human ADCK5, His-tagged | E.coli | His | 1-169a.a. | |
Human | ADCK5-11HCL | Recombinant Human ADCK5 lysate | HEK293 | N/A | ||
Human | ADCK5-905HF | Recombinant Full Length Human ADCK5 Protein, GST-tagged | In Vitro Cell Free System | GST | 169 amino acids | |
Homo sapiens (Human) | RFL35043HF | Recombinant Full Length Human Uncharacterized Aarf Domain-Containing Protein Kinase 5(Adck5) Protein, His-Tagged | E.coli expression system | His | Full Length (1-580) | |
Mus musculus (Mouse) | RFL10245MF | Recombinant Full Length Mouse Uncharacterized Aarf Domain-Containing Protein Kinase 5(Adck5) Protein, His-Tagged | E.coli expression system | His | Full Length (1-582) | |
Zebrafish | ADCK5-7997Z | Recombinant Zebrafish ADCK5 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ADCK5 involved in several pathways and played different roles in them. We selected most pathways ADCK5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCK5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ADCK5 has several biochemical functions, for example, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCK5 itself. We selected most functions ADCK5 had, and list some proteins which have the same functions with ADCK5. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | PENK;HDHD3;BCAS2;TTLL6;KRTAP19-5;GBP2;YIPF2;NOP10;FAM134C |
protein serine/threonine kinase activity | MKNK1;BRAF;SRPK2;PIK3CG;SNRK;AURKA;SPEG;STK38;PRKY |
ADCK5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCK5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCK5.
NOTCH2NL; Dlg4; RHOD; HSPA6; TNS2; Junb
- Q&As
- Reviews
Q&As (13)
Ask a questionADCK5 protein may be a target for drug development aimed at improving CoQ10 biosynthesis and mitochondrial function. However, more research is needed to fully understand the role of ADCK5 protein in these processes and to identify potential drug targets.
ADCK5 protein has been shown to play a critical role in CoQ10 biosynthesis, which is important for energy production and mitochondrial function. Therapeutic applications of ADCK5 protein may include the treatment of conditions related to CoQ10 deficiency or mitochondrial dysfunction, such as neurodegenerative diseases, muscle disorders, and heart disease.
There is currently no evidence to suggest that ADCK5 protein supplementation can improve athletic performance. While CoQ10 supplements may be helpful in some cases of mitochondrial dysfunction, their effects on athletic performance have not been well-established.
While ADCK5 protein plays a role in cellular energy production and mitochondrial function, there is no evidence to suggest that ADCK5 protein supplementation can improve cognitive function. However, CoQ10 supplements have been studied for their potential benefits for cognitive function and neurological disorders, and further research is needed to understand the potential role of ADCK5 protein in these conditions.
ADCK5 protein is being studied in various research settings to better understand its role in CoQ10 biosynthesis and mitochondrial function. This includes studies using cell-based models, animal models, and genetic analyses of patients with mitochondrial disorders or CoQ10 deficiency. Researchers are also exploring the potential therapeutic effects of ADCK5 protein and CoQ10 supplementation on various conditions.
While ADCK5 protein is involved in the pathogenesis of PHSP, it is not yet clear whether it can be used as a therapeutic target for the treatment of this condition. However, research is ongoing to explore the potential use of ADCK5 and CoQ10 biosynthesis pathway for the treatment of PHSP.
ADCK5 protein is expressed in many tissues throughout the body, but it is primarily found in tissues with high energy demands, such as the heart, liver, and skeletal muscles. It is also expressed in the brain and nervous system, indicating its potential role in neurological functions.
At present, there is insufficient evidence to support the use of ADCK5 protein as a biomarker for disease diagnosis or prognosis. However, further research may reveal its potential utility as a biomarker for certain conditions, particularly those that involve mitochondrial dysfunction.
Yes, mutations in the ADCK5 gene have been associated with a rare form of progressive hereditary spastic paralysis (PHSP), which is a neurological disorder that affects the spinal cord and causes muscle weakness and stiffness.
Currently, there are no clinical trials for ADCK5 protein therapy, but research is ongoing to explore the potential therapeutic applications of ADCK5 protein or the CoQ10 biosynthesis pathway. It is possible that clinical trials may be developed in the future, particularly for diseases that involve mitochondrial dysfunction.
ADCK5 protein activity is regulated by various factors, including the availability of its substrate (p-aminobenzoate), as well as other enzymes and cofactors involved in the CoQ10 biosynthesis pathway. Additionally, ADCK5 can be phosphorylated, which can affect its enzymatic activity and stability.
Currently, there are no clinical trials specifically focused on ADCK5 protein. However, some clinical trials are investigating the potential therapeutic effects of CoQ10 supplements on various conditions, including Parkinson's disease, heart failure, and muscular dystrophy.
There is currently no evidence to suggest that ADCK5 protein supplementation can improve mitochondrial function. CoQ10 supplements have been studied for their potential benefits for mitochondrial function and energy metabolism, but the effects of ADCK5 protein supplementation are not yet understood.
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