ARPIN
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Zebrafish
- HEK293
- HEK293T
- Human Cells
- Mammalian Cell
- C
- Myc
- DDK
- His
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ARPIN-606H | Recombinant Human ARPIN Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | ARPIN-82HCL | Recombinant Human ARPIN lysate | HEK293 | N/A | ||
Human | ARPIN-121H | Recombinant Human ARPIN Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | C-Myc/DDK | ||
Human | ARPIN-151H | Recombinant Human ARPIN Protein, His-tagged | Human Cells | His | ||
Mouse | Arpin-1728M | Recombinant Mouse Arpin Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Zebrafish | ARPIN-2522Z | Recombinant Zebrafish ARPIN | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ARPIN involved in several pathways and played different roles in them. We selected most pathways ARPIN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ARPIN has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPIN itself. We selected most functions ARPIN had, and list some proteins which have the same functions with ARPIN. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
protein binding | DTNB;CLN5;ZNF207;STRADB;ZW10;PIK3CB;SSRP1;WDR77;TUBGCP4 |
ARPIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPIN here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPIN.
TRIM27; NIF3L1; AP4M1
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, ARPIN is conserved in various species, including mammals, birds, reptiles, and even some invertebrates. This conservation suggests that it plays an important role in regulating actin cytoskeleton dynamics throughout evolution.
ARPIN plays a crucial role in regulating cell migration. By inhibiting the Arp2/3 complex, it reduces the formation of branched actin networks at the leading edge of migrating cells. This influences the organization of the actin cytoskeleton, lamellipodia formation, and overall cell motility.
Yes, several proteins have been identified as interacting partners for ARPIN. These include the Arp2/3 complex, which is the main target of ARPIN's inhibitory action, as well as other actin-binding proteins and signaling molecules involved in actin dynamics regulation. Examples of interacting proteins include WASP, WAVE, cortactin, and cofilin.
Yes, changes in ARPIN expression levels can influence actin cytoskeleton organization. Overexpression of ARPIN leads to reduced actin branching, resulting in altered actin filament architecture and cell morphology. On the other hand, decreased ARPIN expression or activity may promote excessive actin polymerization and branching, affecting cellular processes that rely on proper actin cytoskeleton dynamics.
While not extensively studied, dysregulation of ARPIN has been proposed to contribute to various pathological conditions. Altered expression or activity of ARPIN has been implicated in cancer metastasis, neuronal development disorders, and immune cell dysfunction, among others.
The potential therapeutic targeting of ARPIN is an area of active research. Modulating the activity of ARPIN could have implications for diseases such as cancer, where disruption of actin dynamics is frequently observed. However, more studies are needed to evaluate the feasibility and effectiveness of targeting ARPIN for therapeutic purposes.
Customer Reviews (3)
Write a reviewThis cutting-edge technique allows for the visualization and characterization of protein structures at the atomic level, providing insights into their function and potential therapeutic targets.
Its exceptional performance in ELISA assays makes it a reliable tool for detecting and quantifying specific target molecules with high sensitivity and specificity.
the ARPIN protein has demonstrated its efficacy in protein electron microscopy structure analysis.
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