Active Recombinant Colony Stimulating Factor 2 (Granulocyte-Macrophage)
Cat.No. : | CSF2-648C |
Product Overview : | GMCSF Canine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 128 amino acids and having a molecular mass of 14.2 kDa. GM-CSF is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CSF2-648C |
Description : | GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
Source : | Canine |
Host : | Escherichia Coli. |
Form : | GMCSF was lyophilized after extensive dialysis against 1x PBS pH= 7.4μ0.1. |
Purity : | Greater than 96.0% as determined by 1. Analysis by RP-HPLC. 2. Analysis by SDS-PAGE. |
Bio-activity : | The ED50 as calculated by the dose-dependant stimulation of the proliferation of human TF1 erythroleukemic cells is typically 1-4 ng/ml. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Solubility : | It is recommended to reconstitute the lyophilized GMCSF in sterile deionized water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Amino acid sequence : | APTRSPTLVT RPSQHVDAIQ EALSLLNNSN DVTAVMNKAV KVVSEVFDPE GPTCLETRLQ LYKEGLQGSL TSLKNPLTMM ANHYKQHCPP TPESPCATQN INFKSFKENL KDFLFNIPFD CWKPVKK. |
Storage : | It is recommended to reconstitute the lyophilized GMCSF in sterile 18Mμ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Canis lupus familiaris ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; GM-CS; granulocyte-macrophage colony-stimulating factor; CSF; colony-stimulating factor |
Gene ID : | 403923 |
mRNA Refseq : | NM_001003245 |
Protein Refseq : | NP_001003245 |
UniProt ID : | P48749 |
Pathway : | Amoebiasis; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; HTLV-I infection; Hematopoietic cell lineage; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Rheumatoid arthritis; T cell receptor signaling pathway |
Products Types
◆ Recombinant Protein | ||
Csf2-49M | Recombinant Active Mouse CSF2 Protein, His-tagged(N-ter) | +Inquiry |
CSF2-28H | Active Recombinant Human CSF2 Protein (Ala18-Glu144), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CSF2-46H | Active Recombinant Human CSF2 Protein | +Inquiry |
CSF2-155C | Active Recombinant Human CSF2 Protein | +Inquiry |
CSF2-47M | Active Recombinant Mouse CSF2 Protein | +Inquiry |
◆ Lysates | ||
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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