Recombinant Full Length Human C4BPB Protein
Cat.No. : | C4BPB-43HF |
Product Overview : | Recombinant full length Human C4 binding protein with N terminal proprietary tag; predicted MWt: 53.35 kDa including the tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 53.350kDa inclusive of tags |
Protein Length : | 252 amino acids |
AA Sequence : | MFFWCACCLM VAWRVSASDE HCPELPPVDN SIFVAKEVEG QILGTYVCIK GYHLVGKKTL FCNASKEWDN TTTECRLGHC PDPVLVNGEF SSSGPVNVSD KITFMCNDHY ILKGSNRSQC LEDHTWAPPF PICKSRDCDP PGNPVHGYFE GNNFTLGSTI SYYCEDRYYL VGVQEQQCVD GEWSSALPVC KLIQEAPKPE CEKALLAFQE SKNLCEAMEN FMQQLKESGM TMEELKYSLE LKKAELKAKL L |
Purity : | Proprietary Purification |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
Storage Buffer : | pH: 8.00. Constituents: 0.3% Glutathione, 0.79% Tris HCl. |
Gene Name : | C4BPB complement component 4 binding protein, beta [ Homo sapiens ] |
Official Symbol : | C4BPB |
Synonyms : | C4BPB; complement component 4 binding protein, beta; C4BP, complement component 4 binding protein, beta; C4b-binding protein beta chain; C4b binding protein; beta chain; complement component 4 binding protein |
Gene ID : | 725 |
mRNA Refseq : | NM_000716 |
Protein Refseq : | NP_000707 |
MIM : | 120831 |
UniProt ID : | P20851 |
Products Types
◆ Recombinant Protein | ||
C4BPB-137H | Recombinant Human C4BPB Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
C4BPB-0054H | Recombinant Human C4BPB Protein, GST-Tagged | +Inquiry |
C4BPB-474H | Recombinant Human C4BPB Protein, His (Fc)-Avi-tagged | +Inquiry |
C4BPB-26312TH | Recombinant Human C4BPB | +Inquiry |
C4BPB-10533H | Recombinant Human C4BPB, His-tagged | +Inquiry |
◆ Native Protein | ||
C4BPB-184H | Native Human C4b-Binding Protein | +Inquiry |
◆ Lysates | ||
C4BPB-8036HCL | Recombinant Human C4BPB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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