Recombinant Full Length Human SUMF1 Protein, C-Flag-tagged
Cat.No. : | SUMF1-414HFL |
Product Overview : | Recombinant Full Length Human SUMF1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 37.3 kDa |
AA Sequence : | MAAPALGLVCGRCPELGLVLLLLLL SLLCGAAGSQEAGTGAGAGSLAGSC GCGTPQRPGAHGSSAAAHRY SREANAPGPVPGERQLAHSKMVPIP AGVFTMGTDDPQIKQDGEAPARRVT IDAFYMDAYEVSNTEFEKFV NSTGYLTEAEKFGDSFVFEGMLSEQ VKTNIQQAVAAAPWWLPVKGANWRH PEGPDSTILHRPDHPVLHVS WNDAVAYCTWAGKRLPTEAEWEYSC RGGLHNRLFPWGNKLQPKGQHYANI WQGEFPVTNTGEDGFQGTAP VDAFPPNGYGLYNIVGNAWEWTSDW WTVHHSVEETLNPKGPPSGKDRVKK GGSYMCHRSYCYRYRCAARS QNTPDSSASNLGFRCAADRLPTMDT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | SUMF1 sulfatase modifying factor 1 [ Homo sapiens (human) ] |
Official Symbol : | SUMF1 |
Synonyms : | FGE; UNQ3037; AAPA3037 |
Gene ID : | 285362 |
mRNA Refseq : | NM_182760.4 |
Protein Refseq : | NP_877437.2 |
MIM : | 607939 |
UniProt ID : | Q8NBK3 |
Products Types
◆ Recombinant Protein | ||
SUMF1-2139H | Recombinant Human SUMF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SUMF1-8869M | Recombinant Mouse SUMF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SUMF1-5827H | Recombinant Human SUMF1 Protein (Ser34-Asp374), C-His tagged | +Inquiry |
SUMF1-5828H | Recombinant Human SUMF1 Protein (Glu113-Ser356), N-His tagged | +Inquiry |
SUMF1-3767Z | Recombinant Zebrafish SUMF1 | +Inquiry |
◆ Lysates | ||
SUMF1-1346HCL | Recombinant Human SUMF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionSUMF1 plays a role in lysosomal function, with implications for lysosomal storage diseases.
SUMF1 influences bone growth and development, potentially affecting skeletal health and disorders.
SUMF1 aids in the degradation of glycosaminoglycans, crucial for the breakdown of these complex molecules.
SUMF1 contributes to cellular detoxification, aiding in the breakdown of potentially harmful substances.
Variations in SUMF1 activity can impact neurological development and function, influencing brain health and disease.
SUMF1 deficiency leads to multiple sulfatase deficiency, disrupting normal metabolism and causing various symptoms.
SUMF1 is essential for the activation of sulfatase enzymes, impacting their role in cellular metabolism.
Customer Reviews (3)
Write a reviewExpert protein engineering support, an invaluable resource for our project.
Consistent western blot results, a lab necessity for our research.
Great protein crystallization service, vital for our structural biology work.
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