Recombinant Full Length Mouse Voltage-Dependent Calcium Channel Gamma-7 Subunit(Cacng7) Protein, His-Tagged

• Cat.No.: RFL36965MF
• Product Overview: Recombinant Full Length Mouse Voltage-dependent calcium channel gamma-7 subunit(Cacng7) Protein (P62956) (1-275aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Mus musculus (Mouse)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length (1-275)
• AA Sequence: MSHCSSRALTLLSSVFGACGLLLVG IAVSTDYWLYMEEGTVLPQNQTTEV KMALHAGLWR VCFFAGREKGRCVASEYFLEPEINL VTENTENILKTVRTATPFPMVSLFL VFTAFVISNI GHIRPQRTILAFVSGIFFILSGLSL VVGLVLYISSINDEVMNRPSSSEQY FHYRYGWSFA FAASSFLLKEGAGVMSVYLFTKRYA EEEMYRPHPAFYRPRLSDCSDYSGQ FLQPEAWRRG RSPSDISSDVSIQMTQNYPPAIKYP DHLHISTSPC
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: Cacng7
• Synonyms: Cacng7; Voltage-dependent calcium channel gamma-7 subunit; Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7
• UniProt ID: P62956

Gene Information

• Gene Name: Cacng7
• Synonyms: Cacng7; Voltage-dependent calcium channel gamma-7 subunit; Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7
• UniProt ID: P62956

Reviews

09/06/2021

Quick and precise protein quantification services.

05/08/2021

Excellent results, highly reliable protein assays.

03/05/2021

Saves time with efficient sample processing.

Q&As

Are there any specific diseases or conditions linked to anomalies in CACNG7?

Dysfunctions or mutations in CACNG7 have been suggested in certain neurological disorders, though more detailed research is essential for specific associations.

How might genetic variants in the CACNG7 gene affect its regulatory role?

Genetic variations in the CACNG7 gene can impact its regulatory influence on calcium channels, potentially affecting neural communication and related processes.

What is the primary biological function of CACNG7 in the context of calcium channels?

CACNG7 acts as an auxiliary subunit, influencing the modulation of activity, trafficking, and surface expression of voltage-gated calcium channels.

Which proteins are known to directly interact with CACNG7?

CACNG7 mainly interacts with the alpha-1 subunit of calcium channels, and may also have associations with other proteins in the channel complex.

How does CACNG7 modulate the activity of associated calcium channels?

Through its interaction, CACNG7 can influence the channel's gating dynamics, cellular localization, and calcium ion permeation characteristics.

In which human tissues or cells is CACNG7 predominantly expressed?

CACNG7 is primarily expressed in neural tissues, with significant levels in particular regions of the brain.

Have any post-translational modifications been documented on CACNG7?

Techniques like mass spectrometry might uncover potential post-translational modifications on CACNG7.