Recombinant Human AAPLN protein, GST-tagged
Cat.No. : | AAPLN-505H |
Product Overview : | Human AAPLN full-length ORF (AAH21104.1, 1 a.a. ~ 122 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 39.16 kDa |
AA Sequence : | MSATWCSPEGQGMGQGPGREVGGNS AASGPASPIRDPCLSEAGLKGPPSA HPRRLCLLHRLVCFSGGLTSIQLSP RTCCSHQWAQLFSPACFPQWRAPGC SLDDSRSLTRIRPVHLPGPSLD |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
SDS-PAGE: |
Gene Name : | APLN apelin [ Homo sapiens ] |
Official Symbol : | APLN |
Synonyms : | APLN; apelin; APEL; XNPEP2; AGTRL1 ligand; APJ endogenous ligand; apelin |
Gene ID : | 8862 |
mRNA Refseq : | NM_017413 |
Protein Refseq : | NP_059109 |
MIM : | 300297 |
UniProt ID : | Q9ULZ1 |
Products Types
◆ Recombinant Protein | ||
APLN-370R | Recombinant Rat APLN Protein, His (Fc)-Avi-tagged | +Inquiry |
APLN-186R | Recombinant Rhesus Macaque APLN Protein, His (Fc)-Avi-tagged | +Inquiry |
Apln-8263M | Recombinant Mouse Apln protein, His & GST-tagged | +Inquiry |
APLN-0102H | Recombinant Human APLN Protein (Ser24-Phe77), N-GST-tagged | +Inquiry |
APLN-714R | Recombinant Rat APLN Protein | +Inquiry |
◆ Lysates | ||
APLN-8792HCL | Recombinant Human APLN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionYes, genetic engineering techniques are often used to produce APLN s.
There may be interactions, and it is recommended to avoid concurrent use of other drugs during use, especially those that affect the cardiovascular system.
APLN promotes cardiovascular protection and anti-tumor effects by binding to APJ receptors.
APLN has potential applications in the treatment of cardiovascular diseases, tumors and metabolic diseases.
APLN can be administered intravenously or subcutaneously.
Dosage should be determined according to the specific situation, it is recommended to consult with a professional doctor.
In the development process, it usually goes through a series of animal experiments to verify its effectiveness and safety.
Common side effects include injection site pain, fever, nausea, etc., but most patients tolerate them well.
APLN can promote blood vessel dilation, inhibit inflammatory response, and facilitate the survival and repair of cardiomyocytes.
There are currently no large-scale clinical trials to confirm its use in cancer treatment, but preliminary research results are promising.
Customer Reviews (3)
Write a reviewWestern blot experiments using this protein can obtain clearly distinguishable bands, indicating that it has high clarity and legibility.
In the course of repeated experiments, the stability of this protein has remained consistent, which provides us with great convenience.
I appreciate the manufacturer's pursuit of product quality, and their product repeatability is very good, which makes me more confident in the experimental results.
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