Recombinant Human ADAMTS8 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ADAMTS8-1511H |
Product Overview : | ADAMTS8 MS Standard C13 and N15-labeled recombinant protein (NP_008968) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 96.3 kDa |
AA Sequence : | MLPAPAAPRWPPLLLLLLLLPLARG APARPAAGGQASELVVPTRLPGSAG ELALHLSAFGKGFVLRLAPDDSFLA PDFKIERLGGSGRATGGERGLRGCF FSGTVNGEPESLAAVSLCRGLSGSF LLDGEEFTIQPQGAGGSLAQPHRLQ RWGPAGARPLPRGPEWEVETGEGQR QERGDHQEDSEEESQEEEAEGASEP PPPLGATSRTKRFVSEARFVETLLV ADASMAAFYGADLQNHILTLMSVAA RIYKHPSIKNSINLMVVKVLIVEDE KWGPEVSDNGGLTLRNFCNWQRRFN QPSDRHPEHYDTAILLTRQNFCGQE GLCDTLGVADIGTICDPNKSCSVIE DEGLQAAHTLAHELGHVLSMPHDDS KPCTRLFGPMGKHHVMAPLFVHLNQ TLPWSPCSAMYLTELLDGGHGDCLL DAPAAALPLPTGLPGRMALYQLDQQ CRQIFGPDFRHCPNTSAQDVCAQLW CHTDGAEPLCHTKNGSLPWADGTPC GPGHLCSEGSCLPEEEVERPKPVVD GGWAPWGPWGECSRTCGGGVQFSHR ECKDPEPQNGGRYCLGRRAKYQSCH TEECPPDGKSFREQQCEKYNAYNYT DMDGNLLQWVPKYAGVSPRDRCKLF CRARGRSEFKVFEAKVIDGTLCGPE TLAICVRGQCVKAGCDHVVDSPRKL DKCGVCGGKGNSCRKVSGSLTPTNY GYNDIVTIPAGATNIDVKQRSHPGV QNDGNYLALKTADGQYLLNGNLAIS AIEQDILVKGTILKYSGSIATLERL QSFRPLPEPLTVQLLTVPGEVFPPK VKYTFFVPNDVDFSMQSSKERATTN IIQPLLHAQWVLGDWSECSSTCGAG WQRRTVECRDPSGQASATCNKALKP EDAKPCESQLCPLTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 [ Homo sapiens (human) ] |
Official Symbol : | ADAMTS8 |
Synonyms : | ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAM TS8; FLJ41712; METH2; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM-TS8; |
Gene ID : | 11095 |
mRNA Refseq : | NM_007037 |
Protein Refseq : | NP_008968 |
MIM : | 605175 |
UniProt ID : | Q9UP79 |
Products Types
◆ Recombinant Protein | ||
ADAMTS8-29H | Recombinant Human ADAMTS8 Protein, MYC/DDK-tagged | +Inquiry |
Adamts8-1531M | Recombinant Mouse Adamts8 Protein, Myc/DDK-tagged | +Inquiry |
ADAMTS8-281H | Recombinant Human ADAMTS8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTS8-0160H | Recombinant Human ADAMTS8 Protein (Leu832-Leu889), N-His-tagged | +Inquiry |
ADAMTS8-3009H | Recombinant Human ADAMTS8, His-tagged | +Inquiry |
◆ Lysates | ||
ADAMTS8-9027HCL | Recombinant Human ADAMTS8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionADAMTS8 shows anti-angiogenesis and inhibition of endothelial cell production
ADAMTS8 is used in more studies of heart and cardiovascular diseases
ADAMTS8 used to be called METH-2.
ADAMTS8 is predominantly expressed in the lungs and heart
Pre-structural domains, metalloproteinase structural domains, disintegrin-like structural domains, central thrombospondin-like motifs, cysteine-rich structural domains, spacer region structural domains and C-terminal motifs
Customer Reviews (3)
Write a reviewThe technician modified my experimental protocol so that my experiment went smoothly.
Very good after-sales service to get my experiments going!
The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.
Ask a Question for All ADAMTS8 Products
Required fields are marked with *
My Review for All ADAMTS8 Products
Required fields are marked with *
Inquiry Basket