Recombinant Human ADCK1, GST-tagged
Cat.No. : | ADCK1-96H |
Product Overview : | Recombinant human ADCK1 (18-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Description : | ADCK1 belongs to the protein kinase superfamily, ADCK protein kinase family that contains a protein kinase domain. The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrates it would phosphorylate. An important paralog of this gene is ADCK5. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~84 kDa |
Purity : | >75% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.05 ug/ul |
Gene Name : | ADCK1 aarF domain containing kinase 1 [ Homo sapiens ] |
Official Symbol : | ADCK1 |
Synonyms : | ADCK1; aarF domain containing kinase 1; uncharacterized aarF domain-containing protein kinase 1; FLJ39600; |
Gene ID : | 57143 |
mRNA Refseq : | NM_001142545 |
Protein Refseq : | NP_001136017 |
UniProt ID : | Q86TW2 |
Chromosome Location : | 14q24 |
Function : | ATP binding; kinase activity; nucleotide binding; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
ADCK1-333M | Recombinant Mouse ADCK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADCK1-66R | Recombinant Rhesus Macaque ADCK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADCK1-320H | Recombinant Human ADCK1 Protein, GST-tagged | +Inquiry |
ADCK1-3564C | Recombinant Chicken ADCK1 | +Inquiry |
ADCK1-6625Z | Recombinant Zebrafish ADCK1 | +Inquiry |
◆ Lysates | ||
ADCK1-10HCL | Recombinant Human ADCK1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (16)
Ask a questionIt is possible that ADCK1 protein may interact with other drugs or medications, especially those that affect mitochondrial function or oxidative stress. More research is needed to determine any potential interactions and their implications.
ADCK1 protein has been shown to regulate oxidative stress and protect against DNA damage, which are key factors in the development and progression of cancer. It may therefore have potential as a therapeutic target for the treatment of cancer. However, more research is needed to determine the effectiveness and safety of this approach.
There are no ongoing clinical trials using ADCK1 protein as a treatment. However, there are several preclinical studies investigating its potential therapeutic applications in various diseases.
ADCK1 protein may have potential benefits as a treatment due to its ability to regulate mitochondrial function and oxidative stress response, which are important factors in many diseases. Additionally, it may be able to improve energy production and cell survival, particularly in cells affected by mitochondrial dysfunction.
The safety of ADCK1 protein for human use has not been fully assessed, as it is still in the preclinical research phase. More studies are needed to determine the potential side effects and risks associated with its use in humans.
ADCK1 protein plays a role in mitochondrial function and oxidative stress response, which are critical processes in many diseases. It is thought to regulate the function of complex I in the electron transport chain, which is essential for generating energy in cells.
It is unclear whether ADCK1 protein can be administered orally, as it may be degraded in the digestive system and may not reach the target tissues effectively. Other administration methods, such as injection or inhalation, may be more effective.
ADCK1 protein can be produced using recombinant DNA technology, in which the gene encoding the protein is inserted into a host cell, such as a bacteria or yeast, to produce large quantities of the protein. Alternatively, it can be purified from natural sources, such as human tissues or cells.
One of the main challenges in the development of ADCK1 protein as a therapeutic agent is the delivery of the protein to the specific tissues and cells where it is needed. Another challenge is the potential for adverse effects, which may arise if the protein is not carefully targeted or if it interacts with other cellular processes. Finally, there may be regulatory challenges in the development and approval of a new therapeutic agent based on ADCK1 protein.
ADCK1 protein has been studied for its potential therapeutic applications in a variety of diseases, including neurodegenerative disorders, cancer, and metabolic disorders.
Neurodegenerative diseases such as Parkinson's and Alzheimer's are associated with mitochondrial dysfunction and oxidative stress. ADCK1 protein has been shown to regulate mitochondrial function and protect against oxidative stress, and may therefore have potential as a therapeutic target for these diseases. However, more research is needed to determine the effectiveness and safety of this approach.
While ADCK1 protein is not currently being developed as a drug, research is ongoing to explore its potential therapeutic applications and its role in various diseases. It is possible that future developments may lead to the use of ADCK1 protein as a drug.
One of the main challenges of using ADCK1 protein as a treatment is its stability and delivery to target tissues. Additionally, more research is needed to fully understand its safety and efficacy as a therapeutic agent in humans.
The method of administration may vary depending on the disease being treated and the specific formulation of ADCK1 protein. Potential methods of administration include injection, inhalation, or oral administration, although more research is needed to determine the most effective method of delivery.
ADCK1 protein has been shown to play a role in metabolic regulation and may therefore have potential as a therapeutic target for metabolic disorders, such as diabetes and obesity. However, more research is needed to determine the effectiveness and safety of this approach.
ADCK1 protein may have potential therapeutic applications for diseases involving mitochondrial dysfunction or oxidative stress, including neurodegenerative diseases, metabolic disorders, and cancer.
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