Active Recombinant Human C2 protein(Met1-Leu752), His-tagged
Cat.No. : | C2-6878H |
Product Overview : | Recombinant Human complement component 2 (C2) precursor (NP_000054.2) (Met 1-Leu 752) was expressed in HEK293 with a C-terminal polyhistidine tag. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-His |
Protein length : | Met1-Leu752 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5, 5'Dithiobis (2-nitrobenzoic acid) (DTNB). The specific activity is >100 pmoles/min/μg. |
Molecular Mass : | The single-chain form of recombinant human complement component C2 comprises 743 amino acids and has a calculated molecular mass of 82.5 kDa. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 97 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | C2 complement component 2 [ Homo sapiens ] |
Official Symbol : | C2 |
Synonyms : | C2; complement component 2; complement C2; C3/C5 convertase; complement component C2; CO2; DKFZp779M0311; |
Gene ID : | 717 |
mRNA Refseq : | NM_000063 |
Protein Refseq : | NP_000054 |
MIM : | 613927 |
UniProt ID : | P06681 |
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◆ Native Protein | ||
C2-98H | Active Native Human C2 Protein | +Inquiry |
◆ Lysates | ||
C2-001MCL | Recombinant Mouse C2 cell lysate | +Inquiry |
C2-3068HCL | Recombinant Human C2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, drugs targeting C2 or the complement system are being explored as potential treatments for autoimmune diseases to regulate the immune response.
Yes, the absence or dysfunction of C2 protein can be indicative of immune system disorders, and its levels can be assessed for diagnostic purposes.
Understanding C2's role in immune activation may contribute to vaccine design, potentially enhancing the effectiveness of vaccines by targeting the complement system.
Abnormal activation of the complement system, including C2, is associated with some autoimmune diseases where the immune system mistakenly attacks the body's own cells.
Yes, genetic variations can affect C2 protein expression and function, leading to variations in immune response among individuals.
Customer Reviews (3)
Write a reviewThe C2 protein comes highly recommended for its excellent performance in various research applications.
It has demonstrated exceptional effectiveness in WB experiments, showcasing its reliability and precision in detecting and quantifying specific targets.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
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