Recombinant Human DNM1L Protein Pre-coupled Magnetic Beads

• Cat.No.: DNM1L-777H-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Human
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: DNM1L dynamin 1 like [ Homo sapiens (human) ]
• Official Symbol: DNM1L
• Synonyms: DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV
• Gene ID: 10059
• mRNA Refseq: NM_012062.5
• Protein Refseq: NP_036192.2
• MIM: 603850
• UniProt ID: O00429

Reviews

12/10/2020

Increase yield and purity and improve production efficiency in biotechnology production.

10/22/2019

Good fluorescence labeling performance in light microscopy technology, which is helpful for cell imaging studies.

06/18/2019

In vaccine research, it has been found that it can induce immune protective effect and has potential for disease prevention.

Q&As

Does a mutation in the DNM1L gene cause a genetic predisposition?

A mutation in the DNM1L gene may have a genetic predisposition, meaning that the mutation is more likely to occur in a patient's family member.

What is the relationship between DNM1L and neuronal connectivity and synaptic function?

DNM1L is involved in the regulation of neuronal connections and synaptic function, especially in the endocytosis and release process of synaptic vesicles, thereby affecting the transmission of neural signals.

What is the inheritance pattern of DNM1L gene mutations?

DNM1L gene mutations can be transmitted in different genetic ways such as autosomal dominant, dominant negative, and dominant homosexual, depending on the type and location of the mutation.

Which diseases are DNM1L gene mutations associated with?

DNM1L gene mutations are associated with a number of neurological-related diseases, including Charcot-Marie-Tooth disease, multiple system atrophy, intellectual disability, and movement disorders.

What is the relationship between DNM1L gene mutations and neurodegenerative diseases?

Mutations in the DNM1L gene may be associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and Huntington's disease.

How to assess the impact of DNM1L gene mutations on disease prognosis?

Through long-term follow-up and clinical data analysis of patients, the impact of DNM1L gene mutations on disease prognosis, such as age of onset, disease progression and quality of life, can be evaluated.