Recombinant Human DUSP4 protein, His-tagged

• Cat.No.: DUSP4-2645H
• Product Overview: Recombinant Human DUSP4 protein(80-181 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 80-181 aa
• AA Sequence: SVSLEQILPAEEEVRARLRSGLYSA VIVYDERSPRAESLREDSTVSLVVQ ALRRNAERTDICLLKGGYERFSSEY PEFCSKTKALAAIPPPVPPSATEPL DL
• Purity: 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: DUSP4 dual specificity phosphatase 4 [ Homo sapiens ]
• Official Symbol: DUSP4
• Synonyms: DUSP4; dual specificity phosphatase 4; dual specificity protein phosphatase 4; HVH2; MAP kinase phosphatase 2; MKP 2; TYP; VH1 homologous phosphatase 2; dual specificity protein phosphatase hVH2; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 2; MKP2; MKP-2
• Gene ID: 1846
• mRNA Refseq: NM_001394
• Protein Refseq: NP_001385
• MIM: 602747
• UniProt ID: Q13115

Reviews

08/16/2022

The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

07/21/2022

Very good after-sales service to get my experiments going!

02/04/2022

The technician modified my experimental protocol so that my experiment went smoothly.

Q&As

How is DUSP4 involved in the signaling pathway?

DUSP4 inactivates MAPKs by dephosphorylating them and thus performs an important function in the MAPK signaling pathway

What is DUSP4 also known as?

DUSP4 also known as mitogen-activated protein kinase phosphatase 2

Which membrane is recommended for DUSP4 protein for WB?

You can choose PVDF membrane.

What diseases is DUSP4 involved in?

DUSP4 is involved in diseases such as laryngeal, breast and colorectal cancer

What are the effects of overexpression of DUSP4?

In colon cancer, overexpression of DUSP4 may lead to increased proliferation of tumor cells through stimulation of growth-promoting genes such as Myc and cell cycle protein D1