Recombinant Human ELAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ELAC1-2236H |
Product Overview : | ELAC1 MS Standard C13 and N15-labeled recombinant protein (NP_061166) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 40 kDa |
AA Sequence : | MSMDVTFLGTGAAYPSPTRGASAVV LRCEGECWLFDCGEGTQTQLMKSQL KAGRITKIFITHLHGDHFFGLPGLL CTISLQSGSMVSKQPIEIYGPVGLR DFIWRTMELSHTELVFHYVVHELVP TADQCPAEELKEFAHVNRADSPPKE EQGRTILLDSEENSYLLFDDEQFVV KAFRLFHRIPSFGFSVVEKKRPGKL NAQKLKDLGVPPGPAYGKLKNGISV VLENGVTISPQDVLKKPIVGRKICI LGDCSGVVGDGGVKLCFEADLLIHE ATLDDAQMDKAKEHGHSTPQMAATF AKLCRAKRLVLTHFSQRYKPVALAR EGETDGIAELKKQAESVLDLQEVTL AEDFMVISIPIKKTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ELAC1 elaC ribonuclease Z 1 [ Homo sapiens (human) ] |
Official Symbol : | ELAC1 |
Synonyms : | ELAC1; elaC ribonuclease Z 1; elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); RNase Z 1; tRNase ZS; tRNase Z 1; deleted in Ma29; ribonuclease Z 1; tRNA 3 endonuclease 1; elaC homolog protein 1; tRNA 3 processing endoribonuclease; FLJ59261; |
Gene ID : | 55520 |
mRNA Refseq : | NM_018696 |
Protein Refseq : | NP_061166 |
MIM : | 608079 |
UniProt ID : | Q9H777 |
Products Types
◆ Recombinant Protein | ||
ELAC1-3227H | Recombinant Human ELAC1 Protein, GST-tagged | +Inquiry |
Elac1-520M | Recombinant Mouse Elac1 Protein, MYC/DDK-tagged | +Inquiry |
ELAC1-2729M | Recombinant Mouse ELAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ELAC1-96H | Recombinant Human ELAC1, His-tagged | +Inquiry |
ELAC1-5120M | Recombinant Mouse ELAC1 Protein | +Inquiry |
◆ Lysates | ||
ELAC1-6639HCL | Recombinant Human ELAC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionELAC1 protein is involved in maintaining mitochondrial function, and mutations in the ELAC1 gene can contribute to mitochondrial disorders.
Clinical trials investigating the role of ELAC1 protein in mitochondrial disorders are currently underway, aiming to develop targeted therapies.
As of now, there are no specific treatments targeting ELAC1 protein for mitochondrial disorders, but ongoing research may lead to future therapeutic approaches.
In addition to pontocerebellar hypoplasia and mitochondrial disorders, mutations in ELAC1 gene have been linked to infantile hypertrophic cardiomyopathy.
ELAC1 protein plays a role in mitochondrial RNA processing, which is essential for proper cardiac function. Mutations in ELAC1 gene can lead to cardiomyopathy.
Customer Reviews (3)
Write a reviewThe ELAC1 Protein exhibits remarkable stability and functionality, making it an optimal choice for a wide range of applications in various fields.
Its exceptional purity and consistency have consistently yielded reliable and reproducible results, ensuring the accuracy and reliability of my research outcomes.
Their prompt and knowledgeable assistance has been instrumental in overcoming hurdles and has significantly contributed to the success of my research.
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