Recombinant Human RAB13, His-tagged

• Cat.No.: RAB13-31040TH
• Product Overview: Recombinant full length Human RAB13 with N terminal His tag; 220 amino acids with tag, Predicted MWt 24.7 kDa.

Specification

• Description: RAB13 (Ras-related protein Rab-13) belongs to the small GTPase superfamily.
• Protein length: 200 amino acids
• Conjugation: HIS
• Molecular Weight: 24.700kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:20% Glycerol, 0.32% Tris HCl, 0.02% DTT, 1.17% Sodium chloride, 0.03% EDTA
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMAKAY DHLFKLLLIGDSGVGKTCLIIRFAE DNFNNTYISTIGIDFKIRTVDIEGK KIKLQVWDTAGQERFKTITTAYYRG AMGIILVYDITDEKSFENIQNWMKS IKENASAGVERLLLGNKCDMEAKRK VQKEQADKLAREHGIRFFETSAKSS MNVDEAFSSLARDILLKSGGRRSGN GNKPPSTDLKTCDKKNTNKC
• Sequence Similarities: Belongs to the small GTPase superfamily. Rab family.

Gene Information

• Gene Name: RAB13 RAB13, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB13
• Synonyms: RAB13; RAB13, member RAS oncogene family; ras-related protein Rab-13
• Gene ID: 5872
• mRNA Refseq: NM_002870
• Protein Refseq: NP_002861
• MIM: 602672
• Uniprot ID: P51153
• Chromosome Location: 1q21.2
• Pathway: Tight junction, organism-specific biosystem; Tight junction, conserved biosystem
• Function: GTP binding; GTPase activity; nucleotide binding

Reviews

08/24/2022

It is very suitable for testing the rate of enzymatic reactions, and it performs very well.

12/23/2021

RAB13 has a good labeling effect and can be used for fluorescent labeling, etc.

11/25/2020

The clearance rate is high and the harm to the human body is small.

Q&As

What are the mutation types of RAB13?

The mutation types of RAB13 include point mutations, insertions, and deletions. Some of these mutations may cause dysfunction of RAB13, while others may affect its interaction with other proteins.

Who is at high risk of RAB13 mutations?

For people at high risk of RAB13 mutations, including those with cancer or other RAB13-related diseases, genetic testing can help doctors diagnose the condition more accurately and develop a corresponding treatment plan.

Can RAB13 mutations assess the impact of RAB13 mutations on disease progression?

The impact of RAB13 mutations on disease progression can be assessed through in-depth analysis of the patient's genomic data. This can help doctors better understand the patient's condition and develop more effective treatment plans.

How can bioinformatics methods analyze the impact of RAB13 mutations on disease?

Its effect on disease can be predicted by comparing the structure and sequence of mutant and wild-type proteins. This can help doctors better understand the patient's condition and develop more effective treatment plans.

How should treatment strategies for patients with RAB13 mutations be considered in clinical practice?

In clinical practice, treatment strategies for patients with RAB13 mutations need to consider the patient's specific condition, genotype, and treatment goals. Doctors can develop a personalized treatment plan based on the patient's actual situation to improve the treatment effect and maximize the patient's quality of life.

How can I detect the expression level of RAB13?

The expression level of RAB13 can be detected by immunohistochemistry, western blotting, real-time PCR, etc. These methods can detect protein or mRNA levels of RAB13 in tissues or cells to assess changes in its expression in disease.