Recombinant Human SYT3 protein, His-tagged

• Cat.No.: SYT3-2792H
• Product Overview: Recombinant Human SYT3 protein(241-590 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 241-590 aa
• AA Sequence: QPDPSSEERPPALPLPLPGGEEKAK LIGQIKPELYQGTGPGGRRSGGGPG SGEAGTGAPCGRISFALRYLYGSDQ LVVRILQAMDLPAKDSNGFSDPYVK IYLLPDRKKKFQTKVHRKTLNPVFN ETFQFSVPLAELAQRKLHFSVYDFD RFSRHDLIGQVVLDNLLELAEQPPD RPLWRDIVEGGSEKADLGELNFSLC YLPTAGRLTVTIIKASNLKAMDLTG FSDPYVKASLISEGRRLKKRKTSIK KNTLNPTYNEALVFDVAPESVENVG LSIAVVDYDCIGHNEVIGVCRVGPD AADPHGREHWAEMLANPRKPVEHWH QLVEEKTVTSFTKGSKGLSEKENSE
• Purity: 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: SYT3 synaptotagmin III [ Homo sapiens ]
• Official Symbol: SYT3
• Synonyms: SytIII
• Gene ID: 84258
• mRNA Refseq: NM_032298.2
• Protein Refseq: NP_115674.1
• MIM: 600327
• UniProt ID: Q9BQG1

Reviews

07/18/2021

Its purity and consistency enable accurate and precise data analysis, ensuring the integrity of my research outcomes.

02/09/2017

the SYT3 protein's exceptional quality, reliability, and the manufacturer's unparalleled technical support make it a prime choice for researchers seeking to delve into the intricacies of angiogenesis, vascular development, and related fields.

07/10/2016

As a researcher utilizing the SYT3 protein in my trials, I have been highly impressed with its numerous advantages that significantly contribute to the success of my experimental endeavors.

Q&As

How does SYT3 contribute to the regulation of calcium signaling in neurons?

SYT3's calcium-binding properties are essential for its role in synaptic vesicle fusion, contributing to the finely tuned calcium signaling necessary for proper neuronal function.

How can SYT3 protein be utilized in diagnostics?

SYT3 levels or mutations might serve as biomarkers for neurological disorders, aiding in the development of diagnostic tools to identify and understand these conditions.

Are there any genetic mutations associated with SYT3 and neurological disorders?

Research suggests that genetic variations in SYT3 may be linked to certain neurological conditions, providing insights into potential genetic markers for susceptibility.

Can SYT3 be a target for drug development?

Explore the potential of SYT3 as a target for drug development, considering its role in neurotransmitter release and synaptic function.

Are there any ongoing clinical trials targeting SYT3 for therapeutic interventions?

Investigate current research and clinical trials focused on modulating SYT3 function as a potential therapeutic strategy for neurological disorders.