Recombinant Mouse Syt3 Protein, Myc/DDK-tagged

• Cat.No.: Syt3-6260M
• Product Overview: Purified recombinant protein of mouse full-length synaptotagmin III (Syt3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ca2+ sensor involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain. Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 63.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Syt3 synaptotagmin III [ Mus musculus (house mouse) ]
• Official Symbol: Syt3
• Synonyms: Syt3; synaptotagmin III; sytIII; AI385753; synaptotagmin-3
• Gene ID: 20981
• mRNA Refseq: NM_016663
• Protein Refseq: NP_057872
• UniProt ID: O35681

Reviews

07/18/2021

Its purity and consistency enable accurate and precise data analysis, ensuring the integrity of my research outcomes.

02/09/2017

the SYT3 protein's exceptional quality, reliability, and the manufacturer's unparalleled technical support make it a prime choice for researchers seeking to delve into the intricacies of angiogenesis, vascular development, and related fields.

07/10/2016

As a researcher utilizing the SYT3 protein in my trials, I have been highly impressed with its numerous advantages that significantly contribute to the success of my experimental endeavors.

Q&As

How does SYT3 contribute to the regulation of calcium signaling in neurons?

SYT3's calcium-binding properties are essential for its role in synaptic vesicle fusion, contributing to the finely tuned calcium signaling necessary for proper neuronal function.

How can SYT3 protein be utilized in diagnostics?

SYT3 levels or mutations might serve as biomarkers for neurological disorders, aiding in the development of diagnostic tools to identify and understand these conditions.

Are there any genetic mutations associated with SYT3 and neurological disorders?

Research suggests that genetic variations in SYT3 may be linked to certain neurological conditions, providing insights into potential genetic markers for susceptibility.

Can SYT3 be a target for drug development?

Explore the potential of SYT3 as a target for drug development, considering its role in neurotransmitter release and synaptic function.

Are there any ongoing clinical trials targeting SYT3 for therapeutic interventions?

Investigate current research and clinical trials focused on modulating SYT3 function as a potential therapeutic strategy for neurological disorders.