Recombinant Human SYT3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SYT3-1880H
• Product Overview: SYT3 MS Standard C13 and N15-labeled recombinant protein (NP_115674) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Ca2+ sensor involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain. Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 63.3 kDa
• AA Sequence: MSGDYEDDLCRRALILVSDLCARVR DADTNDRCQEFNDRIRGYPRGPDAD ISVSLLSVIVTFCGIVLLGVSLFVS WKLCWVPWRDKGGSAVGGGPLRKDL GPGVGLAGLVGGGGHHLAAGLGGHP LLGGPHHHAHAAHHPPFAELLEPGS LGGSDTPEPSYLDMDSYPEAAAAAV AAGVKPSQTSPELPSEGGAGSGLLL LPPSGGGLPSAQSHQQVTSLAPTTR YPALPRPLTQQTLTSQPDPSSEERP PALPLPLPGGEEKAKLIGQIKPELY QGTGPGGRRSGGGPGSGEAGTGAPC GRISFALRYLYGSDQLVVRILQAMD LPAKDSNGFSDPYVKIYLLPDRKKK FQTKVHRKTLNPVFNETFQFSVPLA ELAQRKLHFSVYDFDRFSRHDLIGQ VVLDNLLELAEQPPDRPLWRDIVEG GSEKADLGELNFSLCYLPTAGRLTV TIIKASNLKAMDLTGFSDPYVKASL ISEGRRLKKRKTSIKKNTLNPTYNE ALVFDVAPESVENVGLSIAVVDYDC IGHNEVIGVCRVGPDAADPHGREHW AEMLANPRKPVEHWHQLVEEKTVTS FTKGSKGLSEKENSETRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SYT3 synaptotagmin III [ Homo sapiens (human) ]
• Official Symbol: SYT3
• Synonyms: SYT3; synaptotagmin 3; SytIII; synaptotagmin-3; synaptotagmin III
• Gene ID: 84258
• mRNA Refseq: NM_032298
• Protein Refseq: NP_115674
• MIM: 600327
• UniProt ID: Q9BQG1

Reviews

07/18/2021

Its purity and consistency enable accurate and precise data analysis, ensuring the integrity of my research outcomes.

02/09/2017

the SYT3 protein's exceptional quality, reliability, and the manufacturer's unparalleled technical support make it a prime choice for researchers seeking to delve into the intricacies of angiogenesis, vascular development, and related fields.

07/10/2016

As a researcher utilizing the SYT3 protein in my trials, I have been highly impressed with its numerous advantages that significantly contribute to the success of my experimental endeavors.

Q&As

How does SYT3 contribute to the regulation of calcium signaling in neurons?

SYT3's calcium-binding properties are essential for its role in synaptic vesicle fusion, contributing to the finely tuned calcium signaling necessary for proper neuronal function.

How can SYT3 protein be utilized in diagnostics?

SYT3 levels or mutations might serve as biomarkers for neurological disorders, aiding in the development of diagnostic tools to identify and understand these conditions.

Are there any genetic mutations associated with SYT3 and neurological disorders?

Research suggests that genetic variations in SYT3 may be linked to certain neurological conditions, providing insights into potential genetic markers for susceptibility.

Can SYT3 be a target for drug development?

Explore the potential of SYT3 as a target for drug development, considering its role in neurotransmitter release and synaptic function.

Are there any ongoing clinical trials targeting SYT3 for therapeutic interventions?

Investigate current research and clinical trials focused on modulating SYT3 function as a potential therapeutic strategy for neurological disorders.