Recombinant Mouse ALG6 Protein, His (Fc)-Avi-tagged
Cat.No. : | ALG6-469M |
Product Overview : | Recombinant Mouse ALG6 with His (Fc)-Avi tag was expressed and purified |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Mouse |
Tag : | His (Fc)-Avi |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | ≥85% by SDS-PAGE |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | PBS buffer |
Gene Name : | Alg6 asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase) [ Mus musculus ] |
Official Symbol : | ALG6 |
Gene ID : | 320438 |
mRNA Refseq : | NM_001081264.1 |
Protein Refseq : | NP_001074733.1 |
UniProt ID : | Q3TAE8 |
Products Types
◆ Recombinant Protein | ||
ALG6-286R | Recombinant Rat ALG6 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALG6-1549M | Recombinant Mouse ALG6 Protein | +Inquiry |
ALG6-630R | Recombinant Rat ALG6 Protein | +Inquiry |
ALG6-1117Z | Recombinant Zebrafish ALG6 | +Inquiry |
ALG6-466H | Recombinant Human ALG6 Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (16)
Ask a questionNo studies have confirmed whether ALG6 is involved in mitochondrial glucose metabolism, and more studies are needed to prove it.
Overexpression or knockout of ALG6 can negatively affect cellular glycosylation and the stability of ER and Golgi bodies, but the specific effects need to be further explored.
It is mainly distributed in the endoplasmic reticulum (ER) and the Golgi apparatus.
ALG6 mutation may lead to the occurrence and development of some metabolic diseases such as CDG, and further investigation is needed to confirm its role in metabolic diseases.
ALG6 is involved in several biological processes including protein glycosylation, ER and Golgi body sugar metabolism.
ALG6 plays an important role in protein glycosylation pathway, participating in the synthesis and modification of sugar chains.
ALG6 plays an important role in some neurological diseases, such as central nervous system dysplasia, leading to symptoms such as mental retardation.
At present, there is no direct evidence that ALG6 is related to the occurrence and development of cancer, but glycosylation plays an important role in metabolism and disease development, so it may be relevant to related diseases.
The regulates the expression of glycosylase and the balance of glycosylation reaction by interacting with other glycosylated enzymes such as ALG5 and ALG3.
A number of inhibitors have been developed that target ALG6 and inhibit its glycosylation activity, thereby interfering with its function in cellular processes.
ALG6 interacts with members of the glycosylase family, such as ALG5 and ALG3, and other related proteins to jointly regulate the glycosylation process of proteins.
Although there are currently no studies demonstrating the function of ALG6 in non-cellular autophagy pathways, there are indications that it may be involved in the TCA cycle and gluconeogenic pathways.
ALG6 mutations can have adverse effects on embryonic development and may therefore be associated with a number of fetal diseases.
ALG6 gene contains 14 exons, and its expression is influenced by multiple regulatory elements and signaling pathways.
ALG6 selectively catalyzes the synthesis and modification of sugar chains and plays an important role in the binding selectivity of glycosylase family members to substrate proteins.
This is mainly distributed in the endoplasmic reticulum and Golgi apparatus in mammalian cells.
Customer Reviews (4)
Write a reviewCan increase yield and purity and improve production efficiency in biotechnology production.
ALG6 has therapeutic effects on specific disease models and is promising as a new drug candidate.
Laboratory personnel feedback ALG6 is easy to operate, can meet the experimental needs, and has a good cost performance.
Have good fluorescence labeling performance in light microscopy techniques, which is helpful for cell imaging studies.
Ask a Question for All ALG6 Products
Required fields are marked with *
My Review for All ALG6 Products
Required fields are marked with *
Inquiry Basket