Recombinant Mouse ASCC1 Protein

• Cat.No.: ASCC1-2022M
• Product Overview: Recombinant Mouse ASCC1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Ascc1 activating signal cointegrator 1 complex subunit 1 [ Mus musculus ]
• Official Symbol: ASCC1
• Gene ID: 69090
• mRNA Refseq: NM_001199187.2
• Protein Refseq: NP_001186116.1
• UniProt ID: Q9D8Z1

Reviews

11/25/2022

the use of ASCC1 protein in my research offers significant advantages in detecting cell death processes and investigating coagulation and thrombosis mechanisms.

05/24/2018

The manufacturer's support and expertise further enhance the utility of ASCC1 in my experimental work, ensuring reliable and high-quality results.

11/13/2017

This collaborative partnership greatly contributes to the success of my research projects and facilitates meaningful contributions to the scientific community.

Q&As

How is ASCC1 localization regulated within the cell?

ASCC1 is primarily localized in the nucleus of cells, where it functions in gene expression regulation. It is believed to shuttle between the nucleus and cytoplasm upon specific cellular signaling events.

Does ASCC1 have any post-translational modifications?

The post-translational modifications of ASCC1 have not been extensively studied. However, it is possible that ASCC1 undergoes modifications such as phosphorylation or acetylation, which can regulate its function.

Does ASCC1 have any role in DNA repair processes?

Yes, ASCC1 is involved in DNA repair processes as part of the ASC-1 complex. It participates in the repair of DNA double-strand breaks, contributing to genome stability.

In which tissues or cell types is ASCC1 expressed?

ASCC1 is expressed in a wide range of tissues and cell types, including but not limited to the brain, liver, heart, and skeletal muscle.

Is there any association between ASCC1 and human diseases?

Currently, there are no known human diseases directly associated with ASCC1. However, dysregulation of transcriptional coactivation complexes, in which ASCC1 is involved, can contribute to various diseases.

Can ASCC1 be targeted for therapeutic interventions or drug discovery?

Given the limited understanding of ASCC1's specific role in diseases, it is currently uncertain if it can be directly targeted for therapeutic interventions or drug discovery.

What are the known interacting partners of ASCC1?

ASCC1 interacts with various proteins and transcription factors, such as ATF2, TAF12, and TRIM28, to form the ASC-1 complex and regulate gene expression.