Recombinant Mouse ATP5B protein, His-SUMO & Myc-tagged

• Cat.No.: ATP5B-2567M
• Product Overview: Recombinant Mouse ATP5B protein(P56480)(230-529aa), fused to N-terminal His tag and SUMO tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His-SUMO & Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 52.8 kDa
• Protein length: 230-529aa
• AA Sequence: YSVFAGVGERTREGNDLYHEMIESG VINLKDATSKVALVYGQMNEPPGAR ARVALTGLTVAEYFRDQEGQDVLLF IDNIFRFTQAGSEVSALLGRIPSAV GYQPTLATDMGTMQERITTTKKGSI TSVQAIYVPADDLTDPAPATTFAHL DATTVLSRAIAELGIYPAVDPLDST SRIMDPNIVGNEHYDVARGVQKILQ DYKSLQDIIAILGMDELSEEDKLTV SRARKIQRFLSQPFQVAEVFTGHMG KLVPLKETIKGFQQILAGEYDHLPE QAFYMVGPIEEAVAKADKLAEEHGS
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Gene Information

• Gene Name: Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit [ Mus musculus ]
• Official Symbol: ATP5B
• Synonyms: ATP5B; ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit; ATP synthase subunit beta, mitochondrial; mitochondrial ATP synthase, H+ transporting F1 complex beta subunit; ATP synthase, H+ transporting mitochondrial F1 complex, alpha subunit
• Gene ID: 11947
• mRNA Refseq: NM_016774
• Protein Refseq: NP_058054

Reviews

05/22/2020

The outstanding quality of proteins lies in their strong biological activity and their high purity during production, which is really rare.

04/25/2020

ATP5B has a very short half-life and shows a very high clearance rate, which makes its biological activity more stable.

04/07/2019

Because the production process is efficient and environmentally friendly, recombinant proteins can be produced on a large scale without negative environmental impacts.

Q&As

What is the frequency of ATP5B mutations?

ATP5B gene mutation frequency may be different in different diseases and populations, which needs further study.

How about the link between ATP5B protein and neurological diseases?

It plays an important role in the nervous system and is associated with certain nervous system diseases such as Parkinson's disease and cerebral ischemia.

How are ATP5B mutations associated with disease?

This gene mutations may lead to abnormal protein structure or function, which in turn affects the physiological function of the protein and is associated with specific diseases.

What are the regulatory mechanisms of ATP5B?

ATP5B expression and function are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.

How to evaluate the effect of ATP5B gene mutation on disease?

Assessment of the effect of ATP5B mutations on disease often requires a comprehensive analysis of gene sequencing, protein function studies, and clinical and epidemiological studies.

In which tissues or organs is ATP5B highly expressed?

It is highly expressed in multiple tissues and organs, especially metabolically active tissues such as heart, liver, and brain.