Recombinant Rat ADCK3 Protein

• Cat.No.: ADCK3-514R
• Product Overview: Recombinant Rat ADCK3 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rat
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Adck3 aarF domain containing kinase 3 [ Rattus norvegicus ]
• Official Symbol: ADCK3
• Gene ID: 360887
• mRNA Refseq: NM_001013185.1
• Protein Refseq: NP_001013203.1
• UniProt ID: Q5BJQ0

Q&As

What are the potential therapeutic applications of ADCK3 protein?

ADCK3 protein may have potential therapeutic applications in various diseases, including Parkinson's disease, breast cancer, and other conditions that are linked to CoQ10 deficiency. It may also be useful as a target for developing drugs that modulate CoQ10 biosynthesis.

Are there any limitations to the use of ADCK3 protein in therapy?

One limitation to the use of ADCK3 protein in therapy is its stability and delivery to the target tissues. It is also unclear whether it can be administered orally or if it needs to be delivered via injection or inhalation. Additionally, more studies are needed to determine its safety, efficacy, and potential interactions with other drugs or medications.

Can ADCK3 protein be used in cancer therapy?

ADCK3 protein has been shown to play a role in cell proliferation and migration and may have a potential role in cancer therapy. However, more studies are needed to determine its safety and efficacy.

What potential therapeutic applications does ADCK3 protein have?

ADCK3 protein has been studied for its potential therapeutic applications in various disorders, including mitochondrial diseases, cancer, and neurodegenerative disorders.

Are there any drugs that target ADCK3 protein?

Currently, there are no drugs that directly target ADCK3 protein. However, there are drugs that indirectly affect the biosynthesis of CoQ10, such as statins, which are commonly used to lower cholesterol levels.

Are there any clinical trials underway that focus on ADCK3 protein?

There are currently no clinical trials underway that focus on ADCK3 protein. However, there are ongoing studies investigating CoQ10 supplementation in various conditions, including heart disease and neurodegenerative disorders.

Is ADCK3 protein only found in humans?

No, ADCK3 protein is found in various species, including humans, mice, rats, and zebrafish.

Are there any risks associated with the use of ADCK3 protein therapeutically?

The use of ADCK3 protein as a therapeutic agent has not been extensively studied, so there may be potential risks and side effects that are not yet known. Additionally, using ADCK3 protein to directly modify CoQ10 levels may not be as effective or safe as other methods of increasing CoQ10 levels, such as taking CoQ10 supplements.

How can ADCK3 protein be used in neurodegenerative disorder therapy?

ADCK3 protein has been shown to play a role in the regulation of cellular stress response pathways and may have a potential role in treating neurodegenerative disorders.

Can ADCK3 protein be used as a biomarker for certain diseases?

Yes, studies have shown that ADCK3 protein levels may be decreased in patients with certain diseases, including Parkinson's disease and breast cancer. Therefore, it may have potential as a biomarker for these diseases.

How can ADCK3 protein be used to treat mitochondrial diseases?

Mitochondrial diseases are caused by a defect in mitochondrial function. ADCK3 protein has been shown to play a role in mitochondrial protein synthesis, and therefore it may have a potential role in treating mitochondrial diseases.

Can ADCK3 protein be used to diagnose CoQ10 deficiency?

ADCK3 protein levels may provide indirect information about CoQ10 levels in the body, but it is not a direct diagnostic tool for CoQ10 deficiency. Diagnosis of CoQ10 deficiency usually requires specific tests that measure CoQ10 levels in blood or tissues.