Recombinant Zebrafish TCF7L2

• Cat.No.: TCF7L2-8855Z
• Product Overview: Recombinant Zebrafish TCF7L2 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) [ Danio rerio (zebrafish) ]
• Official Symbol: TCF7L2
• Gene ID: 30510
• mRNA Refseq: NM_131259
• Protein Refseq: NP_571334
• UniProt ID: Q71G54

Reviews

02/28/2021

Exceptional expertise, elevates our research outcomes.

10/27/2018

Exemplary service, vital for our studies.

07/17/2017

Timely and accurate results, invaluable for research.

Q&As

How does TCF7L2 interact with other transcription factors and signaling molecules?

TCF7L2 works in concert with other transcription factors and signaling molecules to regulate gene expression.

How do genetic variations in the TCF7L2 gene affect its function and contribute to disease susceptibility?

Genetic variations in TCF7L2 can significantly impact its function, increasing susceptibility to diabetes and other conditions.

What are the implications of altered TCF7L2 activity in cancer biology?

Altered TCF7L2 activity is associated with various cancers, affecting tumor growth and metastasis.

What is TCF7L2's function in Wnt signaling pathway and its impact on cell proliferation and differentiation?

In the Wnt signaling pathway, TCF7L2 regulates genes involved in cell growth, proliferation, and differentiation.

What potential therapeutic strategies could target TCF7L2 in various diseases, including diabetes and cancer?

Targeting TCF7L2 in therapies could offer new approaches in managing diabetes and certain cancers.

What is the primary role of TCF7L2 in gene regulation and cellular signaling?

TCF7L2 is a transcription factor that regulates gene expression, playing a crucial role in various cellular processes.

How does TCF7L2 influence the development and progression of diabetes, particularly type 2 diabetes?

It is strongly linked to type 2 diabetes risk, influencing insulin secretion and glucose metabolism.