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Home > Products > Recombinant Proteins > Recombinant Human ALDH2 protein, MYC/DDK-tagged

Recombinant Human ALDH2 protein, MYC/DDK-tagged

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"ALDH2" Related Products.
By Species
Human(7)
Mouse(4)
Rat(4)
By Source
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By Tag
GST(1)
His(6)
MYC/DDK(1)
N/A(2)
Cat.No.:
ALDH2-130H
Product Overview:
Recombinant Human ALDH2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description:
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Source:
HEK293
Species:
Human
Tag:
MYC/DDK
Form:
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass:
54.4 kDa
Purity:
> 80% as determined by SDS-PAGE and Coomassie blue staining
Notes:
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration:
>50 ug/mL as determined by microplate BCA method


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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