Recombinant Human Aldehyde Dehydrogenase 1 Family, Member L1, His-tagged
Cat.No. : | ALDH1L1-491H |
Product Overview : | Recombinant Human ALDH1L1protein was expressed as 6-his-tagged fusion protein by E. coli and purifiedby Ni-sepharose. The purified protein was resolved in 1M PBS (58mMNa2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.) added with 300mM Imidazole and 0.7% Sarcosyl,15%glycerol. MW= 44 kDa. |
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Cat. No. : | ALDH1L1-491H |
Description : | ALDH1L1 encoded bythis gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, andwater to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to thealdehyde dehydrogenase family and is responsible for formate oxidation invivo. Deficiencies in ALDH1L1 can result in an accumulation of formate andsubsequent methanol poisoning. |
Host : | E. coli |
Antigen peptideregion : | 157-505aa |
Molecular Weight : | 44 kDa |
Full length : | False |
Storage : | Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided. |
Gene Name : | ALDH1L1 aldehyde dehydrogenase1 family, member L1 [ Homo sapiens ] |
Official Symbol : | ALDH1L1 |
Synonyms : | ALDH1L1;aldehyde dehydrogenase 1 family, member L1; FDH; FTHFD; 10-fTHF; cytosolic10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolatedehydrogenase; 10-formyltetrahydrofolate dehydrogenase; aldehydedehydrogenase family 1 member L1; EC 1.5.1.6; DKFZp781N0997;OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700;OTTHUMP00000222724 |
Gene ID : | 10840 |
mRNA Refseq : | NM_012190 |
Protein Refseq : | NP_036322 |
MIM : | 600249 |
UniProt ID : | O75891 |
Chromosome Location : | 3q21.3 |
Pathway : | One CarbonMetabolism; One carbon pool by folate |
Function : | acyl carrieractivity; catalytic activity; cofactor binding; formyltetrahydrofolatedehydrogenase activity; hydroxymethyl-, formyl- and related transferaseactivity; methyltransferase activity; oxidoreductase activity; oxidoreductaseactivity, acting on the aldehyde or oxo group of donors, NAD or NADP asacceptor |
Products Types
◆ Recombinant Protein | ||
Aldh1l1-117M | Recombinant Mouse Aldh1l1 Protein, His-tagged | +Inquiry |
ALDH1L1-275R | Recombinant Rat ALDH1L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Aldh1l1-344M | Recombinant Mouse Aldh1l1 Protein, MYC/DDK-tagged | +Inquiry |
ALDH1L1-130R | Recombinant Rhesus Macaque ALDH1L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALDH1L1-452M | Recombinant Mouse ALDH1L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ALDH1L1-17HCL | Recombinant Human ALDH1L1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe precise role of ALDH1L1 protein in various diseases is still being elucidated, and developing effective therapies targeting this protein presents challenges.
Targeting ALDH1L1 protein may have potential side effects related to its role in folate metabolism and neural stem cell maintenance.
The expression of ALDH1L1 protein can vary significantly across different cancer types, potentially making it a valuable target for personalized therapies.
Research suggests that targeting ALDH1L1 protein could potentially be a strategy for cancer treatment, but further studies are needed to determine its efficacy.
Research suggests that the expression of ALDH1L1 protein may decrease with age, which could have implications for age-related diseases.
Customer Reviews (3)
Write a reviewOne notable advantage of using the ALDH1L1 protein is the outstanding technical support provided by its manufacturer.
The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.
Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.
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