Recombinant Human ALDH1L1 Protein, GST-tagged
Cat.No. : | ALDH1L1-442H |
Product Overview : | Human ALDH1L1 partial ORF ( NP_036322, 803 a.a. - 902 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | EESFGPVMIISRFADGDLDAVLSRA NATEFGLASGVFTRDINKALYVSDK LQAGTVFVNTYNKTDVAAPFGGFKQ SGFGKDLGEAALNEYLRVKTVTFEY |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALDH1L1 aldehyde dehydrogenase 1 family, member L1 [ Homo sapiens ] |
Official Symbol : | ALDH1L1 |
Synonyms : | ALDH1L1; aldehyde dehydrogenase 1 family, member L1; formyltetrahydrofolate dehydrogenase , FTHFD; cytosolic 10-formyltetrahydrofolate dehydrogenase; 10 fTHF; cytosolic 10 formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase; aldehyde dehydrogenase family 1 member L1; FDH; FTHFD; 10-fTHF; DKFZp781N0997; |
Gene ID : | 10840 |
mRNA Refseq : | NM_012190 |
Protein Refseq : | NP_036322 |
MIM : | 600249 |
UniProt ID : | O75891 |
Products Types
◆ Recombinant Protein | ||
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ALDH1L1-452M | Recombinant Mouse ALDH1L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Aldh1l1-117M | Recombinant Mouse Aldh1l1 Protein, His-tagged | +Inquiry |
ALDH1L1-130R | Recombinant Rhesus Macaque ALDH1L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Aldh1l1-344M | Recombinant Mouse Aldh1l1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ALDH1L1-17HCL | Recombinant Human ALDH1L1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe precise role of ALDH1L1 protein in various diseases is still being elucidated, and developing effective therapies targeting this protein presents challenges.
Targeting ALDH1L1 protein may have potential side effects related to its role in folate metabolism and neural stem cell maintenance.
The expression of ALDH1L1 protein can vary significantly across different cancer types, potentially making it a valuable target for personalized therapies.
Research suggests that targeting ALDH1L1 protein could potentially be a strategy for cancer treatment, but further studies are needed to determine its efficacy.
Research suggests that the expression of ALDH1L1 protein may decrease with age, which could have implications for age-related diseases.
Customer Reviews (3)
Write a reviewOne notable advantage of using the ALDH1L1 protein is the outstanding technical support provided by its manufacturer.
The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.
Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.
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