Recombinant Human luteotropic hormone
Cat.No. : | LH-40H |
Product Overview : | Recombinant Human luteotropic hormone(alpha subunit (NP_000726.1) and beta subunit (NP_000885.1) heterodimer) was expressed in CHO. |
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Source : | CHO |
Species : | Human |
Tag : | N/A |
Form : | pH7.4 PBS |
Molecular Mass : | 42-50kDa |
Purity : | >98% as determined by SDS-PAGE. |
Storage : | This product can be stored at -70°C for 36 months; Store at -20°C for 12 months; It can be stored at 2-8°C for 1 month. Avoid repeated freeze-thaw. |
Concentration : | 1mg/ml |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThere can be loss of bone mineral density so men at risk of osteoporosis should be carefully monitored or treated with bisphosphonates.
Inhibitors ablation are reversible.
LH activates extracellular signal-regulated kinase (ERK) and protein kinase B (PKB/AKT) to drive cell proliferation, differentiation and survival in a variety of cell types.
Yes,you can.Activated LHCGR couples to Gαs G-proteins to initiate the adenylyl cyclase, cAMP and protein kinase A (PKA) signaling pathway.
LH act through the luteinizing hormone choriogonadotropin receptor (LHCGR).
Mechanisms include increased sensitivity of hormone receptors, hormone receptor variants, pathway activation without exposure to hormones (constitutive activation) or upregulated downstream survival pathways.
Using a GnRH (or LH-releasing hormone (LHRH)) agonist (GnRHa,LHRHa) such as goserelin or leuprorelin, usually as a monthly depot injection.
Hormone therapy can be used to reduce the size of the primary cancer before radical surgery or radiotherapy, or to reduce the risk of recurrence.
At high hormone and receptor levels, LHCGR couples to Gαq G-proteins to activate phospholipase C and inositol phosphate signaling to increase intracellular Ca2+.
Like all other gonadotropin hormones, are heterodimers consisting of two monomeric glycoproteins that combine to make a functional protein.They share a common α-subunit, with structural and functional specificity conferred through differing β-subunits.
Customer Reviews (5)
Write a reviewExcellent performance in the EMSA experiment.
Useful in experimental models of calcium deficiency in mice.
Apply for yeast double hybrid experiment.
Effectively promote cell proliferation and division.
None cytotoxicity and is beneficial to promote cell growth.
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