Recombinant Human LH Protein, His&GST-tagged
Cat.No. : | LH-2688H |
Product Overview : | Recombinant Human LH Protein (Ala25-Ser116+GGGGS*3+Ser21-Leu141) with N-His&GST tag was expressed in E. coli. |
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Description : | Luteinizing hormone (LH) is one of three glycoprotein anterior pituitary hormones, with follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH) being the other two. |
Source : | E. coli |
Species : | Human |
Tag : | N-His&GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 54.3 kDa Accurate Molecular Mass: 54 kDa |
Protein length : | Ala25-Ser116+GGGGS*3+Ser21-Leu141 |
Purity : | > 80% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Official Symbol : | LH |
Synonyms : | Luteinizing Hormone; LH; ICSH; Lutropin; Interstitial Cell Stimulating Hormone |
Official Symbol : | LH |
Synonyms : | Luteinizing Hormone; LH; ICSH; Lutropin; Interstitial Cell Stimulating Hormone |
Products Types
◆ Recombinant Protein | ||
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LH-2687R | Recombinant Rat LH Protein, His-tagged | +Inquiry |
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LH-43H | Recombinant Human Luteinizing Hormone | +Inquiry |
◆ Native Protein | ||
LH-838H | Active Native Human Luteinizing Hormone | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThere can be loss of bone mineral density so men at risk of osteoporosis should be carefully monitored or treated with bisphosphonates.
Inhibitors ablation are reversible.
LH activates extracellular signal-regulated kinase (ERK) and protein kinase B (PKB/AKT) to drive cell proliferation, differentiation and survival in a variety of cell types.
Yes,you can.Activated LHCGR couples to Gαs G-proteins to initiate the adenylyl cyclase, cAMP and protein kinase A (PKA) signaling pathway.
LH act through the luteinizing hormone choriogonadotropin receptor (LHCGR).
Mechanisms include increased sensitivity of hormone receptors, hormone receptor variants, pathway activation without exposure to hormones (constitutive activation) or upregulated downstream survival pathways.
Using a GnRH (or LH-releasing hormone (LHRH)) agonist (GnRHa,LHRHa) such as goserelin or leuprorelin, usually as a monthly depot injection.
Hormone therapy can be used to reduce the size of the primary cancer before radical surgery or radiotherapy, or to reduce the risk of recurrence.
At high hormone and receptor levels, LHCGR couples to Gαq G-proteins to activate phospholipase C and inositol phosphate signaling to increase intracellular Ca2+.
Like all other gonadotropin hormones, are heterodimers consisting of two monomeric glycoproteins that combine to make a functional protein.They share a common α-subunit, with structural and functional specificity conferred through differing β-subunits.
Customer Reviews (5)
Write a reviewExcellent performance in the EMSA experiment.
Useful in experimental models of calcium deficiency in mice.
Apply for yeast double hybrid experiment.
Effectively promote cell proliferation and division.
None cytotoxicity and is beneficial to promote cell growth.
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