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Recombinant Rat LH Protein, His-tagged

Cat.No. : LH-2687R
Product Overview : Recombinant Rat LH Protein (Leu25-Ser120) with N-His tag was expressed in E. coli.
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Description : Luteinizing hormone (LH) is one of three glycoprotein anterior pituitary hormones, with follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH) being the other two.
Source : E. coli
Species : Rat
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 14.3 kDa
Accurate Molecular Mass: 15 kDa
Protein length : Leu25-Ser120
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
Official Symbol : LH
Synonyms : Luteinizing Hormone; LH; ICSH; Lutropin; Interstitial Cell Stimulating Hormone
Official Symbol : LH
Synonyms : Luteinizing Hormone; LH; ICSH; Lutropin; Interstitial Cell Stimulating Hormone

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can patients with osteoporosis receive LHRH antagonist therapy? 04/14/2023

There can be loss of bone mineral density so men at risk of osteoporosis should be carefully monitored or treated with bisphosphonates.

Is the antagonistic reaction of LH inhibitors reversible? 04/14/2023

Inhibitors ablation are reversible.

Can LH drive proliferation, differentiation, and survival of multiple cell types? 04/14/2023

LH activates extracellular signal-regulated kinase (ERK) and protein kinase B (PKB/AKT) to drive cell proliferation, differentiation and survival in a variety of cell types.

Can the LH signaling pathway be blocked with protein kinase A (PKA) inhibitors? 04/14/2023

Yes,you can.Activated LHCGR couples to Gαs G-proteins to initiate the adenylyl cyclase, cAMP and protein kinase A (PKA) signaling pathway.

By which receptor does LH act? 04/14/2023

LH act through the luteinizing hormone choriogonadotropin receptor (LHCGR).

Why does hormone therapy produce resistance? 04/14/2023

Mechanisms include increased sensitivity of hormone receptors, hormone receptor variants, pathway activation without exposure to hormones (constitutive activation) or upregulated downstream survival pathways.

Can postmenopausal women achieve estrogen suppression without ovarian radiation or surgical removal? 04/14/2023

Using a GnRH (or LH-releasing hormone (LHRH)) agonist (GnRHa,LHRHa) such as goserelin or leuprorelin, usually as a monthly depot injection.

What are the advantages of hormone therapy for cancer? 04/14/2023

Hormone therapy can be used to reduce the size of the primary cancer before radical surgery or radiotherapy, or to reduce the risk of recurrence.

Can I get calcium by increasing my LH level? 04/14/2023

At high hormone and receptor levels, LHCGR couples to Gαq G-proteins to activate phospholipase C and inositol phosphate signaling to increase intracellular Ca2+.

Does LH have the same structure as other gonadotropins? 04/14/2023

Like all other gonadotropin hormones, are heterodimers consisting of two monomeric glycoproteins that combine to make a functional protein.They share a common α-subunit, with structural and functional specificity conferred through differing β-subunits.

Customer Reviews (5)

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Reviews
07/11/2021

    Excellent performance in the EMSA experiment.

    08/14/2020

      Useful in experimental models of calcium deficiency in mice.

      09/15/2019

        Apply for yeast double hybrid experiment.

        04/19/2018

          Effectively promote cell proliferation and division.

          12/11/2016

            None cytotoxicity and is beneficial to promote cell growth.

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