Recombinant Human SLC4A1 Protein Pre-coupled Magnetic Beads

• Cat.No.: SLC4A1-2033H-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Human
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: SLC4A1 solute carrier family 4 member 1 (Diego blood group) [ Homo sapiens (human) ]
• Official Symbol: SLC4A1
• Synonyms: DI; FR; SW; WD; WR; AE1; CHC; SAO; WD1; BND3; EPB3; SPH4; CD233; EMPB3; RTA1A
• Gene ID: 6521
• mRNA Refseq: NM_000342.4
• Protein Refseq: NP_000333.1
• MIM: 109270
• UniProt ID: P02730

Reviews

05/18/2022

Timely delivery, so I got the desired experimental results in the shortest possible time.

05/10/2021

Friendly customer service and detailed answers to all the questions I asked!

12/30/2020

The technicians were very professional and suggested improvements to my experimental program, which allowed the experiment to go smoothly.

Q&As

Where is SLC4A1 mainly expressed?

SLC4A1 is expressed on the erythrocyte membrane and the basement membrane surface of renal type A intercalary cells.

What are the effects of mutations in the SLC4A1?

The reduced amount of SLC4A1 protein following the SLC4A1 mutation makes the erythrocyte membrane less stable and prone to detachment, and the resulting reduction in surface area/volume changes the shape of the erythrocyte from a biconcave disc shape to a spherical shape.

What biological function does SLC4A1 have?

The main function of SLC4A1 is to carry out HCO3-/Cl- transmembrane transport.

What diseases has SLC4A1 been closely associated with the study of?

SLC4A1 has been closely associated with studies of diseases such as distal renal tubular acidosis and hereditary spherocytosis.